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Getting down to the real question: effects of transfusion triggers on long-term survival and quality of life following septic shock

Martin W. Dünser, James A. Russell
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Improving outcomes after critical illness: harder than we thought!

Carol Hodgson, Brian H. Cuthbertson
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Intravenous iron or placebo for anaemia in intensive care: the IRONMAN multicentre randomized blinded trial

Edward Litton, Stuart Baker, Wendy N. Erber, Shannon Farmer, Janet Ferrier, Craig French, Joel Gummer, David Hawkins, Alisa Higgins, Axel Hofmann, Bart De Keulenaer, Julie McMorrow, John K. Olynyk, Toby Richards, Simon Towler, Robert Trengove, Steve Webb
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Long-term outcomes in patients with septic shock transfused at a lower versus a higher haemoglobin threshold: the TRISS randomised, multicentre clinical trial

Sofie L. Rygård, Lars B. Holst, Jørn Wetterslev, Per Winkel, Pär I. Johansson, Jan Wernerman, Anne B. Guttormsen, Sari Karlsson, Anders Perner
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Neurally adjusted ventilatory assist as an alternative to pressure support ventilation in adults: a French multicentre randomized trial

A. Demoule, M. Clavel, C. Rolland-Debord, S. Perbet, N. Terzi, A. Kouatchet, F. Wallet, H. Roze, F. Vargas, C. Guerin, J. Dellamonica, S. Jaber, L. Brochard, T. Similowski
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Nitric oxide administration during paediatric cardiopulmonary bypass: a randomised controlled trial

Christopher James, Johnny Millar, Stephen Horton, Christian Brizard, Charlotte Molesworth, Warwick Butt
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No harm, no benefit: should we give up with neurally adjusted ventilatory assist?

Paolo Navalesi, Federico Longhini
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Restricting volumes of resuscitation fluid in adults with septic shock after initial management: the CLASSIC randomised, parallel-group, multicentre feasibility trial

Peter B. Hjortrup, Nicolai Haase, Helle Bundgaard, Simon L. Thomsen, Robert Winding, Ville Pettilä, Anne Aaen, David Lodahl, Rasmus E. Berthelsen, Henrik Christensen, Martin B. Madsen, Per Winkel, Jørn Wetterslev, Anders Perner
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Comparison of conventional and ultrasound guided techniques of radial artery cannulation in different haemodynamic subsets: a randomised controlled study

Jyoti Burad, Rohit Date, Sonali Kodange, Abdul Hakeem Al Hashim, Karin Nollain
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Focus on adequate antimicrobial treatment and de-escalation in the ICU

Dominique D. Benoit, Gordon Doig, Jean-Francois Timsit
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