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Are systematic reviews and meta-analyses still useful research? No

Sylvie Chevret, Niall D. Ferguson, Rinaldo Bellomo
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Are systematic reviews and meta-analyses still useful research? We are not sure

Morten Hylander Møller, John P. A. Ioannidis, Michael Darmon
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Are systematic reviews and meta-analyses still useful research? Yes

Djillali Annane, Roman Jaeschke, Gordon Guyatt
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Infection-related ventilator-associated complications in ICU patients colonised with extended-spectrum β-lactamase-producing Enterobacteriaceae

François Barbier, Sébastien Bailly, Carole Schwebel, Laurent Papazian, Élie Azoulay, Hatem Kallel, Shidasp Siami, Laurent Argaud, Guillaume Marcotte, Benoît Misset, Jean Reignier, Michaël Darmon, Jean-Ralph Zahar, Dany Goldgran-Toledano, Étienne de Montmollin, Bertrand Souweine, Bruno Mourvillier, Jean-François Timsit
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Paediatric acute kidney injury: can we match therapy with resources around the world?

Akash Deep, Jordan M. Symons, Mignon McCulloch
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Procalcitonin algorithm to guide initial antibiotic therapy in acute exacerbations of COPD admitted to the ICU: a randomized multicenter studyOpen access

Cédric Daubin, Xavier Valette, Fabrice Thiollière, Jean-Paul Mira, Pascal Hazera, Djillali Annane, Vincent Labbe, Bernard Floccard, François Fournel, Nicolas Terzi, Damien Du Cheyron, Jean-Jacques Parienti
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Ted Kolobow

Luciano Gattinoni, Antonio Pesenti, Lorenzo Berra, Robert Bartlett
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Is very short-course antibiotic therapy possible in postoperative intra-abdominal infections? Discussion on “Short-course antibiotic therapy for critically ill patients treated for postoperative intra-abdominal infection: the DURAPOP randomised clinical trial”

Alejandro Suarez-de-la-Rica, Fernando Gilsanz, Emilio Maseda, Philippe Montravers, Sigismond Lasocki, Thomas Lescot, Herve Dupont
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AKI biomarkers are poor discriminants for subsequent need for renal replacement therapy, but do not disqualify them yet

Harm-Jan de Grooth, Jean-Jacques Parienti, Miet Schetz
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Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study)Open access

Tobias Welte, R. Phillip Dellinger, Henning Ebelt, Miguel Ferrer, Steven M. Opal, Mervyn Singer, Jean-Louis Vincent, Karl Werdan, Ignacio Martin-Loeches, Jordi Almirall, Antonio Artigas, Jose Ignacio Ayestarán, Sebastian Nuding, Ricard Ferrer, Gonzalo Sirgo Rodríguez, Manu Shankar-Hari, Francisco Álvarez-Lerma, Reimer Riessen, Josep-Maria Sirvent, Stefan Kluge, Kai Zacharowski, Juan Bonastre Mora,
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