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Volume 45, Number 2 / February, 2019

Systematic Review

Stress ulcer prophylaxis with proton pump inhibitors or histamin-2 receptor antagonists in adult intensive care patients: a systematic review with meta-analysis and trial sequential analysis

Marija Barbateskovic, Søren Marker, Anders Granholm, Carl Thomas Anthon, Mette Krag, Janus Christian Jakobsen, Anders Perner, Jørn Wetterslev, Morten Hylander Møller
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Review

Challenges in severe community-acquired pneumonia: a point-of-view review

Antoni Torres, James D. Chalmers, Charles S. Dela Cruz, Cristina Dominedò, Marin Kollef, Ignacio Martin-Loeches, Michael Niederman, Richard G. Wunderink
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Rationalizing antimicrobial therapy in the ICU: a narrative review

Jean-François Timsit, Matteo Bassetti, Olaf Cremer, George Daikos, Jan de Waele, Andre Kallil, Eric Kipnis, Marin Kollef, Kevin Laupland, Jose-Artur Paiva, Jesús Rodríguez-Baño, Étienne Ruppé, Jorge Salluh, Fabio Silvio Taccone, Emmanuel Weiss, François Barbier
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Original

The diagnostic accuracy of clinical examination for estimating cardiac index in critically ill patients: the Simple Intensive Care Studies-IOpen access

Bart Hiemstra, Geert Koster, Renske Wiersema, Yoran M. Hummel, Pim van der Harst, Harold Snieder, Ruben J. Eck, Thomas Kaufmann, Thomas W. L. Scheeren, Anders Perner, Jørn Wetterslev, Anne Marie G. A. de Smet, Frederik Keus, Iwan C. C. van der Horst
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Influence of the initial level of consciousness on early, goal-directed mobilization: a post hoc analysis

Stefan J. Schaller, Flora T. Scheffenbichler, Somnath Bose, Nicole Mazwi, Hao Deng, Franziska Krebs, Christian L. Seifert, George Kasotakis, Stephanie D. Grabitz, Nicola Latronico, Timothy Houle, Manfred Blobner, Matthias Eikermann
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A multicentre controlled pre–post trial of an implementation science intervention to improve venous thromboembolism prophylaxis in critically ill patients

Henry T. Stelfox, Rebecca Brundin-Mather, Andrea Soo, Jeanna Parsons Leigh, Daniel J. Niven, Kirsten M. Fiest, Christopher James Doig, Danny J. Zuege, Barry Kushner, Fiona Clement, Sharon E. Straus, Deborah J. Cook, Sean M. Bagshaw, Khara M. Sauro
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Tailored multicomponent program for discomfort reduction in critically ill patients may decrease post-traumatic stress disorder in general ICU survivors at 1 year

Pierre Kalfon, Marine Alessandrini, Mohamed Boucekine, Stéphanie Renoult, Marie-Agnès Geantot, Stéphanie Deparis-Dusautois, Audrey Berric, Olivier Collange, Bernard Floccard, Olivier Mimoz, Amour Julien, René Robert, Juliette Audibert, Anne Renault, Arnaud Follin, Didier Thevenin, Nathalie Revel, Marion Venot, René-Gilles Patrigeon, Thomas Signouret, Mélanie Fromentin, Tarek Sharshar, Coralie Vign
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What's New in Intensive Care

Hemoadsorption with CytoSorb®

Elettra C. Poli, Thomas Rimmelé, Antoine G. Schneider
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Future of the ICU: finding treatable needles in the data haystack

Lieuwe D. J. Bos, Elie Azoulay, Ignacio Martin-Loeches
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Infectious diseases: the 10 common truths I never believed

Jordi Rello, Emine Alp, Kalwaje Eshwara Vandana
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The challenge of local consent requirements for global critical care databases

Stuart McLennan, David Shaw, Leo Anthony Celi
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What’s new in the prevention of healthcare-associated infections using chlorhexidine gluconate-impregnated washcloths

Sandrine Dray, Jean-Marie Forel, Laurent Papazian
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Frugal innovation for critical care

Armand Mekontso Dessap
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Understanding the Disease

Understanding hypoxemia on ECCO2R: back to the alveolar gas equation

Jean-Luc Diehl, Alain Mercat, Antonio Pesenti
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Imaging in Intensive Care Medicine

Cerebral fat embolism after intraosseous infusion

Faten May, Jérôme Hodel, Armand Mekontso Dessap, Keyvan Razazi
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The accidental discovery of a tracheal diverticulum

Rosanna Varutti, Fabio Rosa, Umberto Zuccon, Flavio Bassi
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The ‘blinking frog’ ultrasound sign establishes the presence of pretracheal vasculatureOpen access

Pieter R. Tuinman, David van Westerloo, Stefanie Slot, Hugo R. W. Touw
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Blindness as an uncommon complication of Streptococcus pneumoniae systemic infection

R. Clere-Jehl, H. Merdji, D. Derhy, J. Helms
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From the Inside

This is not a drill

Luca Carenzo
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Editorial

Clinical examination: a trigger but not a substitute for hemodynamic evaluation

Daniel De Backer, Antoine Vieillard-Baron
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Observational vs randomized: David vs Goliath for thromboprophylaxis in critically ill patients?

Julie Helms, Julian Bion, Audrey De Jong
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Is chloride worth its salt?

Scott L. Weiss, Franz E. Babl, Stuart R. Dalziel, Fran Balamuth
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Cardiac arrest, gender and resuscitation outcomes

Yigal Helviz, Marcus Ong, Sharon Einav
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Treatment with a polymyxin B filter to capture endotoxin in sepsis patients: is there a signal for therapeutic efficacy?

Peter Pickkers, James A. Russell
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Oxygen and carbon dioxide targets during and after resuscitation of cardiac arrest patients

M. B. Skrifvars, T. M. Olasveengen, Giuseppe Ristagno
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Physiological interventions in cardiac arrest: passing the pilot phaseOpen access

Niklas Nielsen, Alain Cariou, Christian Hassager
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Letter

Mechanism of airway closure in acute respiratory distress syndrome: a possible role of surfactant depletion

Remi Coudroy, Cong Lu, Lu Chen, Alexandre Demoule, Laurent Brochard
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Effect of body position and inclination in supine and prone position on respiratory mechanics in acute respiratory distress syndrome

Mehdi Mezidi, Claude Guérin
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Small-bowel capsule endoscopy for obscure gastrointestinal bleeding in the ICU

Jacques Boutros, Sarah Leblanc, Frédéric Pène
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Correspondence

Assessment of respiratory mechanics during pressure support ventilation? Caution required

Katerina Vaporidi, George Prinianakis, Dimitris Georgopoulos, Claude Guérin
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Correction

Correction to: Physiological interventions in cardiac arrest: passing the pilot phase

Niklas Nielsen, Alain Cariou, Christian Hassager
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