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Volume 42, Number 4 / April, 2016

Focus Editorial

Focus on infection and sepsis in intensive care patients

Ignacio Martin-Loeches, Anders Perner
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Seven-Day Profile Publication

Rapid response team and hospital mortality in hospitalized patients

Boris Jung, Aurelien Daurat, Audrey De Jong, Gerald Chanques, Martin Mahul, Marion Monnin, Nicolas Molinari, Samir Jaber
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Systematic Review

Antithrombin III for critically ill patients: a systematic review with meta-analysis and trial sequential analysis

Mikkel Allingstrup, Jørn Wetterslev, Frederikke B. Ravn, Ann Merete Møller, Arash Afshari
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Incidence and associations of acute kidney injury after major abdominal surgery

M. E. O’Connor, C. J. Kirwan, R. M. Pearse, J. R. Prowle
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Review

Positive and negative effects of mechanical ventilation on sleep in the ICU: a review with clinical recommendations

Nuttapol Rittayamai, Elizabeth Wilcox, Xavier Drouot, Sangeeta Mehta, Alberto Goffi, Laurent Brochard
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Original

Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial

François Lamontagne, Maureen O. Meade, Paul C. Hébert, Pierre Asfar, François Lauzier, Andrew J.E. Seely, Andrew G. Day, Sangeeta Mehta, John Muscedere, Sean M. Bagshaw, Niall D. Ferguson, Deborah J. Cook, Salmaan Kanji, Alexis F. Turgeon, Margaret S. Herridge, Sanjay Subramanian, Jacques Lacroix, Neill K.J. Adhikari, Damon C. Scales, Alison Fox-Robichaud, Yoanna Skrobik, Richard P. Whitlock, Robe
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Plasma levels of danger-associated molecular patterns are associated with immune suppression in trauma patientsOpen access

Kim Timmermans, Matthijs Kox, Michiel Vaneker, Maarten van den Berg, Aaron John, Arjan van Laarhoven, Hans van der Hoeven, Gert Jan Scheffer, Peter Pickkers
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Pre-morbid glycemic control modifies the interaction between acute hypoglycemia and mortality

Moritoki Egi, James S. Krinsley, Paula Maurer, Devendra N. Amin, Tomoyuki Kanazawa, Shruti Ghandi, Kiyoshi Morita, Michael Bailey, Rinaldo Bellomo
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What's New in Intensive Care

Ten reasons to be more attentive to patients when setting the ventilator

Arnaud W. Thille, Ferran Roche-Campo, Laurent Brochard
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What’s new in the quantification of causal effects from longitudinal cohort studies: a brief introduction to marginal structural models for intensivists

S. Bailly, R. Pirracchio, J. F. Timsit
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Can this patient be safely discharged from the ICU?

Andrew A. Kramer, Thomas L. Higgins, Jack E. Zimmerman
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Understanding the Disease

Understanding platelet dysfunction in sepsis

Luca Pigozzi, Jonathan Paul Aron, Jonathan Ball, Maurizio Cecconi
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Imaging in Intensive Care Medicine

Critical illness myopathy and whole body MRI

Aurélien Dinh, Robert Carlier, Alexis Descatha
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Cardiac effect of sodium bicarbonate in sodium-channel blocker poisoning

Malcolm Lemyze, Juliette Masse, Charles Queva, David Huchette
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From the Inside

ICU: a branch of hell?

Ángela Alonso-Ovies, Gabriel Heras La Calle
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Editorial

Rapid response teams improve outcomes: yes

Daryl Jones, Francesca Rubulotta, John Welch
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Rapid response teams improve outcomes: no

Ritesh Maharaj, Henry T. Stelfox
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Rapid response teams improve outcomes: we are not sure

Julia Wendon, Carol Hodgson, Rinaldo Bellomo
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Dealing with phthalates in medical devices: a case of primum non nocere (first do no harm)?

Robert C. Tasker, Richard M. Sharpe
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Association of prior antiplatelet agents with mortality in sepsis patients

Min-Juei Tsai, Chia-Jen Shih, Yung-Tai Chen
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Finally time for rapid response systems to be well MET in Europe?

Markus B Skrifvars, Ignacio Martin-Loeches
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Understanding why clinicians should care about danger-associated molecular patterns

Karim Asehnoune, Richard S. Hotchkiss, Guillaume Monneret
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Letter

Effect of rapid response systems on hospital mortality: a systematic review and meta-analysis

Audrey De Jong, Boris Jung, Aurelien Daurat, Gerald Chanques, Martin Mahul, Marion Monnin, Nicolas Molinari, Samir Jaber
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Sensitivity and specificity of Critical Care Pain Observation Tool used for intubated patients following open-heart surgery

Atefeh Ghanbari, Nasrin Bahadorizadeh, Rabiollah Farmanbar, Ehsan Kazemnejad
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Oral mucosal adverse events with chlorhexidine 2 % mouthwash in ICUOpen access

Nienke L. Plantinga, Bastiaan H. J. Wittekamp, Kris Leleu, Pieter Depuydt, Anne-Marie Van den Abeele, Christian Brun-Buisson, Marc J. M. Bonten
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Impaired dynamics of clot formation and hypofibrinolysis in severe sepsis are coexisting and strictly related

Mauro Panigada, Francesca Sampietro, Camilla L’Acqua, Lucia Zacchetti, Massimo Boscolo Anzoletti, Rossella Bader, Luciano Gattinoni, Armando D’Angelo
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Use of extracorporeal carbon dioxide removal (ECCO2R) in 239 intensive care units: results from a French national survey

B. Deniau, J. D. Ricard, J. Messika, D. Dreyfuss, Stephane Gaudry
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The impact of the Greek socio-economic crisis on ICU patient recruitment

Savvoula Savvidou, Dimitrios Matamis
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Correspondence

Comments on Marik and Hooper: Normocaloric versus hypocaloric feeding on the outcomes of ICU patients: a systematic review and meta-analysis

Militsa Bitzani
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Normocaloric versus hypocaloric feeding in ICU patients: response to comments by Bitzani

Paul E. Marik, Michael H. Hooper
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Response to: Protocols: help for improvement but beware of regression to the mean and mediocrity

Peter Isherwood
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The dose makes the poison

Armand R. J. Girbes, René Robert, Paul E. Marik
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Appropriate positioning of the NAVA catheter

Willem-Jan M. Schellekens, Leo M. A. Heunks
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Medical simulation for ICU staff: does it influence safety of care?

Andrea Cortegiani, Vincenzo Russotto, Cesare Gregoretti, Antonino Giarratano, Massimo Antonelli
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