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Volume 38, Number 12 / December, 2012

Editorial

Randomized controlled trials and practice guidelines: the good, the bad, and the ugly

Charles L. Sprung
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Surpassing boundaries: volatile sedation in the NeuroICU

Federico Villa, Giuseppe Citerio
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Review

Electrical impedance tomography: the holy grail of ventilation and perfusion monitoring?

Steffen Leonhardt, Burkhard Lachmann
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Special Article

Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study

Alexis Tabah, Despoina Koulenti, Kevin Laupland, Benoit Misset, Jordi Valles, Frederico Bruzzi de Carvalho, José Artur Paiva, Nahit Çakar, Xiaochun Ma, Philippe Eggimann, Massimo Antonelli, Marc J. M. Bonten, Akos Csomos, Wolfgang A. Krueger, Adam Mikstacki, Jeffrey Lipman, Pieter Depuydt, Aurélien Vesin, Maité Garrouste-Orgeas, Jean-Ralph Zahar, Stijn Blot, Jean Carlet, Christian Brun-Buisson, Cl
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Original

Low-dose steroids in adult septic shock: results of the Surviving Sepsis Campaign

Brian Casserly, Herwig Gerlach, Gary S. Phillips, Stanley Lemeshow, John C. Marshall, Tiffany M. Osborn, Mitchell M. Levy
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Volatile isoflurane sedation in cerebrovascular intensive care patients using AnaConDa®: effects on cerebral oxygenation, circulation, and pressure

Julian Bösel, Jan C. Purrucker, Frank Nowak, Julian Renzland, Petra Schiller, Eva Benveniste Pérez, Sven Poli, Benjamin Brunn, Werner Hacke, Thorsten Steiner
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Associations of markers of inflammation and coagulation with delirium during critical illness

Timothy D. Girard, Lorraine B. Ware, Gordon R. Bernard, Pratik P. Pandharipande, Jennifer L. Thompson, Ayumi K. Shintani, James C. Jackson, Robert S. Dittus, E. Wesley Ely
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How to implement monitoring tools for sedation, pain and delirium in the intensive care unit: an experimental cohort study

Finn M. Radtke, Anja Heymann, Martin Franck, Friederike Maechler, Tanja Drews, Alawi Luetz, Irit Nachtigall, Klaus-Dieter Wernecke, Claudia D. Spies
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Sleep quality of mechanically ventilated patients sedated with dexmedetomidine

Jun Oto, Katsunori Yamamoto, Shigefumi Koike, Mutsuo Onodera, Hideaki Imanaka, Masaji Nishimura
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Hypertriglyceridemia: a potential side effect of propofol sedation in critical illness

J.-C. Devaud, M. M. Berger, A. Pannatier, P. Marques-Vidal, L. Tappy, N. Rodondi, R. Chiolero, P. Voirol
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Risk factors for hypoglycaemia in neurocritical care patients

Freya M. van Iersel, Arjen J. C. Slooter, Renee Vroegop, Annemiek E. Wolters, Charlotte A. M. Tiemessen, Rik H. J. Rösken, Johannes G. van der Hoeven, Linda M. Peelen, Cornelia W. E. Hoedemaekers
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Pathophysiology of Escherichia coli ventilator-associated pneumonia: implication of highly virulent extraintestinal pathogenic strains

Jonathan Messika, Fatma Magdoud, Olivier Clermont, Dimitri Margetis, Stéphane Gaudry, Damien Roux, Catherine Branger, Didier Dreyfuss, Erick Denamur, Jean-Damien Ricard
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Diaphragm electromyographic activity as a predictor of weaning failure

Martin Dres, Matthieu Schmidt, Alexis Ferre, Julien Mayaux, Thomas Similowski, Alexandre Demoule
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The repeatability of Stewart’s parameters and anion gap in a cohort of critically ill adult patients

Jihad Mallat, Stéphanie Barrailler, Malcolm Lemyze, Younes Benzidi, Florent Pepy, Gaëlle Gasan, Laurent Tronchon, Didier Thevenin
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Cardiac function in Ghanaian children with severe malaria

Samuel B. Nguah, Torsten Feldt, Steffi Hoffmann, Daniel Pelletier, Daniel Ansong, Justice Sylverken, Parisa Mehrfar, Johanna Herr, Christian Thiel, Stephan Ehrhardt, Gerd D. Burchard, Jakob P. Cramer
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Pediatric Original

The relationship between blood lactate concentration, the Paediatric Index of Mortality 2 (PIM2) and mortality in paediatric intensive care

Kevin P. Morris, Phil McShane, John Stickley, Roger C. Parslow
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Copeptin as a marker of relative arginine vasopressin deficiency after pediatric cardiac surgery

Christopher W. Mastropietro, Meredith Mahan, Kevin M. Valentine, Jeff A. Clark, Patrick C. Hines, Henry L. Walters III, Ralph E. Delius, Ashok P. Sarnaik, Noreen F. Rossi
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Vitamin D status in critically ill children

Constance Rippel, Michael South, Warwick W. Butt, Lara S. Shekerdemian
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Experimental

Beneficial effects of stress-dose corticosteroid therapy in canines depend on the severity of staphylococcal pneumonia

Caitlin W. Hicks, Daniel A. Sweeney, Robert L. Danner, Peter Q. Eichacker, Anthony F. Suffredini, Jing Feng, Junfeng Sun, Brad Moriyama, Robert Wesley, Ellen N. Behrend, Steven B. Solomon, Charles Natanson
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Physiological and Technical Notes

Mechanisms of ventilator dependence in children with neuromuscular and respiratory control disorders identified by monitoring diaphragm electrical activity

Miriam R. Fine-Goulden, Naga K. Puppala, Andrew Durward
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Correspondence

A telephone survey of intensive care unit handover practices in the UK

Denosshan Sri
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Focal neurological deficit with tricuspid endocarditis and patent foramen ovale

Julien Pottecher, Pierre-Olivier Ludes, Cornelia Kuhnert, Hélène Petit-Eisenmann, Arnaud Mommerot
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Extracorporeal life support for refractory cardiac arrest: what is a good outcome?

Giulia Maj, Michele De Bonis, Marina Pieri, Giulio Melisurgo, Federico Pappalardo
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Assessment of regional lung mechanics with electrical impedance tomography can determine the requirement for ECMO in patients with severe ARDS

Luigi Camporota, John Smith, Nicholas Barrett, Richard Beale
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Comments on O’Brien et al.: Prevalence and outcome of cirrhosis patients admitted to UK intensive care: a comparison against dialysis-dependent chronic renal failure patients

Nicholas P. Mason, Andrew D. Yeoman
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Prevalence and outcome of cirrhosis patients admitted to UK intensive care: a comparison against dialysis-dependent chronic renal failure patients: Reply to comments by Mason and Yeoman

Alastair O’Brien
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