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Volume 36, Number 6 / June, 2010

Editorial

Toll-like receptors: a link between mechanical ventilation, innate immunity and lung injury?

Pierre Emmanuel Charles, Saber Davide Barbar
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Combined analysis of cardiac output and CVP changes remains the best way to titrate fluid administration in shocked patients

Fabrice Vallée, Arnaud Mari, Anders Perner, Benoît Vallet
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Review

Outcome of acute kidney injury in severe burns: a systematic review and meta-analysis

Nele Brusselaers, Stan Monstrey, Kirsten Colpaert, Johan Decruyenaere, Stijn I. Blot, Eric A. J. Hoste
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Use of dexmedetomidine as a sedative and analgesic agent in critically ill adult patients: a meta-analysis

Jen A. Tan, Kwok M. Ho
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Original

Central venous pressure measurements improve the accuracy of leg raising-induced change in pulse pressure to predict fluid responsiveness

Karim Lakhal, Stephan Ehrmann, Isabelle Runge, Dalila Benzekri-Lefèvre, Annick Legras, Pierre François Dequin, Emmanuelle Mercier, Michel Wolff, Bernard Régnier, Thierry Boulain
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Effects of fluids on microvascular perfusion in patients with severe sepsis

Gustavo Ospina-Tascon, Ana Paula Neves, Giovanna Occhipinti, Katia Donadello, Gustavo Büchele, Davide Simion, Maria-Luisa Chierego, Tatiana Oliveira Silva, Adriana Fonseca, Jean-Louis Vincent, Daniel De Backer
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Fall in circulating mononuclear cell mitochondrial DNA content in human sepsis

Angela Pyle, David J. Burn, Charlotte Gordon, Catherine Swan, Patrick F. Chinnery, Simon V. Baudouin
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The influence of infection sites on development and mortality of ARDS

Chau-Chyun Sheu, Michelle N. Gong, Rihong Zhai, Ednan K. Bajwa, Feng Chen, B. Taylor Thompson, David C. Christiani
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Pneumonia associated with invasive and noninvasive ventilation: an analysis of the German nosocomial infection surveillance system database

Anke Kohlenberg, Frank Schwab, Michael Behnke, Christine Geffers, Petra Gastmeier
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Pharmacokinetics of moxifloxacin in patients with severe sepsis or septic shock

Mathias W. Pletz, Frank Bloos, Olaf Burkhardt, Frank M. Brunkhorst, Stefanie M. Bode-Böger, Jens Martens-Lobenhoffer, Mark W. Greer, Heino Stass, Tobias Welte
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Tracheal pressure and endotracheal tube obstruction can be detected by continuous cuff pressure monitoring: in vitro pilot study

Shai Efrati, Israel Deutsch, Gabriel M. Gurman, Matitiau Noff, Giorgio Conti
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Post-intubation laryngeal injuries and extubation failure: a fiberoptic endoscopic study

Jean-Marc Tadié, Eva Behm, Lucien Lecuyer, Rania Benhmamed, Stéphane Hans, Daniel Brasnu, Jean-Luc Diehl, Jean-Yves Fagon, Emmanuel Guérot
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Whole lung lavage: a unique model for ultrasound assessment of lung aeration changes

Gabriele Via, Daniel Lichtenstein, Francesco Mojoli, Giuseppe Rodi, Luca Neri, Enrico Storti, Catherine Klersy, Giorgio Iotti, Antonio Braschi
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Are home ventilators able to guarantee a minimal tidal volume?

Brigitte Fauroux, Karl Leroux, Jean-Louis Pépin, Frédéric Lofaso, Bruno Louis
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Pediatric Original

Critically ill infants and children with influenza A (H1N1) in pediatric intensive care units in Argentina

Julio A. Farias, Analía Fernández, Ezequiel Monteverde, Nilda Vidal, Pilar Arias, María J. Montes, Gabriela Rodríguez, Mariela Allasia, Maria E. Ratto, Roxana Jaén, Claudia Meregalli, Karina Fiquepron, Ana R. Calvo, Alejandro Siaba, Lidia Albano, Rossana Poterala, Pablo Neira, Andrés Esteban
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Genetic polymorphisms in the endotoxin receptor may influence platelet count as part of the acute phase response in critically ill children

Rachel S. Agbeko, John W. Holloway, Meredith L. Allen, Shu Ye, Katy J. Fidler, John Pappachan, Allan Goldman, David Pontefract, John Deanfield, Nigel J. Klein, Mark J. Peters
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Brief Report

Iatrogenic events contributing to ICU admission: a prospective study

Emmanuelle Mercier, Bruno Giraudeau, Guy Giniès, Dominique Perrotin, Pierre-François Dequin
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Inter-rater reliability of manual muscle strength testing in ICU survivors and simulated patients

Eddy Fan, Nancy D. Ciesla, Alex D. Truong, Vinodh Bhoopathi, Scott L. Zeger, Dale M. Needham
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Diagnostic accuracy of serum hepcidin for iron deficiency in critically ill patients with anemia

Sigismond Lasocki, Gabriel Baron, Fathi Driss, Mark Westerman, Hervé Puy, Isabelle Boutron, Carole Beaumont, Philippe Montravers
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Experimental

Mechanical ventilation modulates Toll-like receptor signaling pathway in a sepsis-induced lung injury model

Jesús Villar, Nuria Cabrera, Milena Casula, Carlos Flores, Francisco Valladares, Mercedes Muros, Lluis Blanch, Arthur S. Slutsky, Robert M. Kacmarek
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Milrinone, dobutamine or epinephrine use in asphyxiated newborn pigs resuscitated with 100% oxygen

Chloë Joynt, David L. Bigam, Gregory Charrois, Laurence D. Jewell, Gregory Korbutt, Po-Yin Cheung
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Age-dependent effects of gradual decreases in cerebral perfusion pressure on the neurochemical response in swine

Bernd Walter, Kristina Aisenpreis, Harald G. Fritz, Jens Soukup, Michael Eiselt, Reinhard Bauer
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Legal and Ethical Issues in Clinical Research

Triaging for adult critical care in the event of overwhelming need

Nigel Eastman, Barbara Philips, Andrew Rhodes
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Physiological and Technical Notes

Transpulmonary thermodilution curves for detection of shunt

Raphael Giraud, Nils Siegenthaler, Chan Park, Sascha Beutler, Karim Bendjelid
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Correspondence

Early enteral nutrition in the ICUOpen access

Ronald Lee Koretz
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Early enteral nutrition in critically ill patients: authors’ response

Gordon S. Doig, Fiona Simpson
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Bedside detection of acute epidural hematoma by transcranial sonography in a head-injured patient

A. Caricato, V. Mignani, C. Sandroni, D. Pietrini
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Tracheotomy cuff inflation and tube displacement

P. Ceriana, G. Bertoli, S. Nava
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The Chiu/Park scale for grading intestinal ischemia–reperfusion: if it ain’t broke don’t fix it!

Mihai Oltean, Michael Olausson
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Reply to Oltean and Olausson

Ke Xuan Liu, Yun Sheng Li, Wen Qi Huang, Shu Qin Chen, Zhong Xin Wang, Jia Xin Liu
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Hydrocortisone therapy for patients with H1N1 influenza A infection

Silvio A. Ñamendys-Silva, Marisol Hernández-Garay
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Corticosteroids for H1N1 associated acute lung injury: is it just wishful thinking?

Jorge I. F. Salluh, Pedro Póvoa
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Reply to Ñamendys-Silva and Salluh

Adolfo Maximo Quispe-Laime, Reba Umberger, Gianfranco Umberto Meduri
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Should we administer sildenafil to patients with acute respiratory distress syndrome? No

Silvio A. Ñamendys-Silva, Marisol Hernández-Garay, Eduardo Rivero-Sigarroa
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There is no place (yet) for routine administration of sildenafil to patients with ARDSOpen access

Alexander D. Cornet, Nicole P. Juffermans
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