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Volume 34, Number 11 / November, 2008

Special Article

Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shockOpen access

Simon Finfer, V. Marco Ranieri, B. Taylor Thompson, Philip S. Barie, Jean-François Dhainaut, Ivor S. Douglas, Bengt Gårdlund, John C. Marshall, Andrew Rhodes
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Editorial

Editors’ comments on a new trial of activated protein C for persistent septic shockOpen access

Jordi Mancebo, Massimo Antonelli
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Science, medicine and industry: are we getting out of the black hole in sepsis research?Open access

Peter M. Suter, Jukka Takala
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Once is not enough: clinical trials in sepsisOpen access

Daniel A. Sweeney, Robert L. Danner, Peter Q. Eichacker, Charles Natanson
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ICU patients: fatter is better?

Wilfred Druml
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Impact of body weight on critically ill patients: a heavy load!!

Andres Esteban, Fernando Frutos-Vivar, Antonio Anzueto
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NAVA: brain over machine?

Franco Laghi
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Systematic Review

The use of propofol for medium and long-term sedation in critically ill adult patients: a meta-analysis

Kwok M. Ho, Joseph Y. Ng
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Review

Immunonutrition in critically ill patients: a systematic review and analysis of the literature

Paul E. Marik, Gary P. Zaloga
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Original

Impact of obesity in mechanically ventilated patients: a prospective study

Jean-Pierre Frat, Valérie Gissot, Stéphanie Ragot, Arnaud Desachy, Isabelle Runge, Christine Lebert, René Robert
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Obesity is associated with increased morbidity but not mortality in critically ill patients

Yasser Sakr, Christian Madl, Daniela Filipescu, Rui Moreno, Johan Groeneveld, Antonio Artigas, Konrad Reinhart, Jean-Louis Vincent
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Physiologic response to varying levels of pressure support and neurally adjusted ventilatory assist in patients with acute respiratory failure

Davide Colombo, Gianmaria Cammarota, Valentina Bergamaschi, Marta De Lucia, Francesco Della Corte, Paolo Navalesi
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Recruitability of the lung estimated by the pressure volume curve hysteresis in ARDS patients

Didier Demory, Jean-Michel Arnal, Marc Wysocki, Stéphane Donati, Isabelle Granier, Gaëlle Corno, Jacques Durand-Gasselin
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Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support

Nektaria Xirouchaki, Eumorfia Kondili, Katerina Vaporidi, George Xirouchakis, Maria Klimathianaki, George Gavriilidis, Evi Alexandopoulou, Maria Plataki, Christina Alexopoulou, Dimitris Georgopoulos
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Intrapulmonary percussive ventilation superimposed on conventional ventilation: bench study of humidity and ventilator behaviour

Jean Dellamonica, Bruno Louis, Aissam Lyazidi, Frédéric Vargas, Laurent Brochard
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Image reconstruction affects computer tomographic assessment of lung hyperinflation

Andreas W. Reske, Harald Busse, Marcelo B. P. Amato, Matthias Jaekel, Thomas Kahn, Peter Schwarzkopf, Dierk Schreiter, Udo Gottschaldt, Matthias Seiwerts
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From the ICU to the ward: cross-checking of the physician’s transfer report by intensive care nurses

Andreas Perren, Patrik Conte, Nunzio De Bitonti, Costanzo Limoni, Paolo Merlani
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Non-invasive assessment of intracranial pressure using ocular sonography in neurocritical care patients

Thomas Geeraerts, Sybille Merceron, Dan Benhamou, Bernard Vigué, Jacques Duranteau
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Antithrombin level and circuit thrombosis during hemofiltration after cardiopulmonary bypass

H. Lanquetot, T. Leprince, S. Ragot, C. Boinot, C. Jayle, R. Robert, L. Macchi
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Sleep monitoring in the intensive care unit: comparison of nurse assessment, actigraphy and polysomnography

Jaime M. Beecroft, Michael Ward, Magdy Younes, Shelley Crombach, Orla Smith, Patrick J. Hanly
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Prognostic value of midregional pro-atrial natriuretic peptide in ventilator-associated pneumonia

Renato Seligman, Jana Papassotiriou, Nils G. Morgenthaler, Michael Meisner, Paulo J. Z. Teixeira
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Pediatric Original

Assessing sedation in critically ill children by bispectral index, auditory-evoked potentials and clinical scales

Adelaida Lamas, Jesús López-Herce, Luis Sancho, Santiago Mencía, Ángel Carrillo, Maria José Santiago, Vicente Martínez
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Safety and efficacy of ultrasound assistance during internal jugular vein cannulation in neurosurgical infants

M. Lamperti, D. Caldiroli, P. Cortellazzi, D. Vailati, A. Pedicelli, F. Tosi, M. Piastra, D. Pietrini
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Brief Report

Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry

Benjamin Maddison, Riccardo Giudici, Enrico Calzia, Christopher Wolff, Charles Hinds, Peter Radermacher, Rupert M. Pearse
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A prospective study of factors influencing the outcome of patients after a Medical Emergency Team review

Paolo Calzavacca, Elisa Licari, Augustine Tee, Moritoki Egi, Michael Haase, Anja Haase-Fielitz, Rinaldo Bellomo
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Correspondence

Opioid and benzodiazepine contributions to etomidate-associated adrenal insufficiency

Harry Daniell
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Opioid and benzodiazepine contributions to etomidate-associated adrenal insufficiency

Jean-François Payen, Marc Vinclair, Christophe Broux, Olivier Chabre
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Auto-reactive myocarditis after percutaneous closure of an atrial septal defect

Cristina Chimenti, Marco Agrusta, Angelo Cioppa, Ester Campopiano, Paolo Rubino, Andrea Frustaci
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Purpura fulminans due to imported falciparum malaria

Philippe Corne, Fabrice Bruneel, Christine Biron-Andreani, Olivier Jonquet
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Potential role of surgery in traumatic focal brain lesions as revealed by functional imaging

Arturo Chieregato, Enrico Fainardi
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