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Does this critically ill patient with delirium require any drug treatment?

Jorge I. F. Salluh| Nicola Latronico
What's New in Intensive Care
Volume 45, Issue 4 / April , 2019

Pages 501 - 504

No abstract available.


  1. Salluh JI, Wang H, Schneider EB et al (2015) Outcome of delirium in critically ill patients: systematic review and meta-analysis. BMJ. https://doi.org/10.1136/bmj.h2538
  2. Khan BA, Perkins AJ, Gao S et al (2017) The confusion assessment method for the ICU-7 Delirium Severity Scale. Crit Care Med. https://doi.org/10.1097/CCM.0000000000002368
  3. Barr J, Fraser GL, Puntillo K et al (2013) Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the Intensive Care Unit: executive summary. Am J Health Syst Pharm. https://doi.org/10.1097/CCM.0b013e3182783b72
  4. Morandi A, Piva S, Ely EW et al (2017) Worldwide survey of the “Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium Monitoring/Management, Early Exercise/Mobility, and Family Empowerment” (ABCDEF) Bundle. Crit Care Med. https://doi.org/10.1097/CCM.0000000000002640
  5. Cavalcanti AB, Bozza FA, Machado FR et al (2016) Effect of a quality improvement intervention with daily round checklists, goal setting, and clinician prompting on mortality of critically ill patients: a randomized clinical trial. JAMA J Am Med Assoc. https://doi.org/10.1001/jama.2016.3463
  6. Barnes-Daly MA, Phillips G, Ely EW (2017) Improving hospital survival and reducing brain dysfunction at seven california community hospitals. Crit Care Med. https://doi.org/10.1097/CCM.0000000000002149
  7. Rosa RG, Tonietto TF, Da Silva DB et al (2017) Effectiveness and safety of an extended icu visitation model for delirium prevention: a before and after study. Crit Care Med. https://doi.org/10.1097/CCM.0000000000002588
  8. Serafim RB, Bozza FA, Soares M et al (2015) Pharmacologic prevention and treatment of delirium in intensive care patients: a systematic review. J Crit Care. https://doi.org/10.1016/j.jcrc.2015.04.005
  9. Neufeld KJ, Yue J, Robinson TN et al (2016) Antipsychotic medication for prevention and treatment of delirium in hospitalized adults: a systematic review and meta-analysis. J Am Geriatr Soc. https://doi.org/10.1111/jgs.14076
  10. van den Boogaard M, Slooter AJC, Brüggemann RJM et al (2018) Effect of haloperidol on survival among critically ill adults with a high risk of delirium. JAMA. https://doi.org/10.1001/jama.2018.0160
  11. Delaney A, Hammond N, Litton E (2018) Preventing delirium in the intensive care unit. JAMA. https://doi.org/10.1016/j.ccc.2012.10.007
  12. Oh ES, Fong TG, Hshieh TT, Inouye SK (2017) Delirium in older persons. JAMA. https://doi.org/10.1001/jama.2017.12067
  13. Skrobik Y, Duprey MS, Hill NS, Devlin JW (2018) Low-dose nocturnal dexmedetomidine prevents ICU delirium: a randomized, placebo-controlled trial. Am J Respir Crit Care Med. https://doi.org/10.1164/rccm.201710-1995oc
  14. Wassenaar A, van den Boogaard M, van Achterberg T et al (2015) Multinational development and validation of an early prediction model for delirium in ICU patients. Intensive Care Med. https://doi.org/10.1007/s00134-015-3777-2
  15. Chevrolet JC, Jolliet P (2007) Clinical review: Agitation and delirium in the critically ill—significance and management. Crit Care 11(3):214
    • View reference on publisher's website
  16. Reade MC, Eastwood GM, Bellomo R et al (2016) Effect of dexmedetomidine added to standard care on ventilator-free time in patients with agitated delirium a randomized clinical trial. JAMA J Am Med Assoc. https://doi.org/10.1001/jama.2016.2707
  17. Latronico N (2018) Haloperidol and delirium in the ICU: the finger pointing to the moon. Intensive Care Med. https://doi.org/10.1007/s00134-018-5276-8

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