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Frugal innovation for critical care

Armand Mekontso Dessap
What's New in Intensive Care
Volume 45, Issue 2 / February , 2019

Pages 252 - 254

No abstract available.


  1. De Backer D, Aldecoa C, Njimi H, Vincent J-L (2012) Dopamine versus norepinephrine in the treatment of septic shock: a meta-analysis*. Crit Care Med 40:725–730. https://doi.org/10.1097/ccm.0b013e31823778ee
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  2. Wilkman E, Kaukonen K-M, Pettilä V et al (2013) Association between inotrope treatment and 90-day mortality in patients with septic shock. Acta Anaesthesiol Scand 57:431–442. https://doi.org/10.1111/aas.12056
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  3. Ricard JD, Markowicz P, Djedaini K et al (1999) Bedside evaluation of efficient airway humidification during mechanical ventilation of the critically ill. Chest 115:1646–1652
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  4. Lacherade J, Auburtin M, Cerf C et al (2005) Impact of humidification systems on ventilator-associated pneumonia: a randomized multicenter trial. Am J Respir Crit Care Med 172:1276–1282
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  5. Lellouche F, Taillé S, Maggiore S et al (2004) Influence of ambient and ventilator output temperatures on performance of heated-wire humidifiers. Am J Respir Crit Care Med 170:1073–1079
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  6. Maitland K, Kiguli S, Opoka RO et al (2011) Mortality after fluid bolus in African children with severe infection. N Engl J Med 364:2483–2495
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  7. Andrews B, Semler MW, Muchemwa L et al (2017) Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial. JAMA 318:1233. https://doi.org/10.1001/jama.2017.10913
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  8. Weyrauch T, Herstatt C (2017) What is frugal innovation? Three defining criteria. J Frugal Innov. https://doi.org/10.1186/s40669-016-0005-y
  9. Basu R, Banerjee P, Sweeny E (2013) Frugal innovation: core competencies to address global sustainability. J Manag Glob Sustain 1:63–82. https://doi.org/10.13185/jm2013.01204
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  10. for the China Critical Care Clinical Trials Group (CCCCTG), Weng L, Zeng X et al (2018) Sepsis-related mortality in China: a descriptive analysis. Intensive Care Med. https://doi.org/10.1007/s00134-018-5203-z
  11. Bhatti YA, Prime M, Harris M et al (2017) The search for the holy grail: frugal innovation in healthcare from low-income or middle-income countries for reverse innovation to developed countries. BMJ Innov 3:212–220. https://doi.org/10.1136/bmjinnov-2016-000186
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  12. Arshad H, Radić M, Radić D (2018) Patterns of frugal innovation in healthcare. Technol Innov Manag Rev 8:28–37. https://doi.org/10.22215/timreview/1150
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  13. Gallah S, Benzerara Y, Tankovic J et al (2018) β LACTA test performance for detection of extended-spectrum β-lactamase-producing Gram-negative bacilli directly on bronchial aspirates samples: a validation study. Clin Microbiol Infect 24:402–408. https://doi.org/10.1016/j.cmi.2017.07.030
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  14. Ait-Oufella H, Bakker J (2016) Understanding clinical signs of poor tissue perfusion during septic shock. Intensive Care Med 42:2070–2072. https://doi.org/10.1007/s00134-016-4250-6
  15. Goudelin M, Evrard B, Dalmay F et al (2018) Diagnostic capability of a next-generation, ultra-miniaturized ultrasound system in patients with cardiopulmonary compromise assessed using basic critical care echocardiography. Intensive Care Med. https://doi.org/10.1007/s00134-018-5225-6

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