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Caution for chlorhexidine gluconate use for oral care: insufficient data

Jean-Damien Ricard| Thiago Lisboa
Editorial
Volume 44, Issue 7 / July , 2018

Pages 1162 - 1164

No abstract available.

References

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  6. Plantinga NL, Wittekamp BHJ, Leleu K et al (2016) Oral mucosal adverse events with chlorhexidine 2% mouthwash in ICU. Intensive Care Med 42:620–621
  7. Deschepper M, Waegeman W, Eeckloo K, Vogelaers D, Blot S (2018) Effects of chlorhexidine gluconate oral care on hospital mortality: a hospital-wide, observational cohort study. Intensive Care Med. https://doi.org/10.1007/s00134-018-5171-3
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  8. Hirata K, Kurokawa A (2002) Chlorhexidine gluconate ingestion resulting in fatal respiratory distress syndrome. Vet Hum Toxicol 44:89–91
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  9. Orito K, Hashida M, Hirata K, Kurokawa A, Shirai M, Akahori F (2006) Effects of single intratracheal exposure to chlorhexidine gluconate on the rat lung. Drug Chem Toxicol 29:1–9
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  10. Xue Y, Zhang S, Yang Y, Lu M, Wang Y, Zhang T, Tang M, Takeshita H (2011) Acute pulmonary toxic effects of chlorhexidine (CHX) following an intratracheal instillation in rats. Hum Exp Toxicol 30:1795–1803
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