Log in | Register

AKI biomarkers are poor discriminants for subsequent need for renal replacement therapy, but do not disqualify them yet

Harm-Jan de Grooth| Jean-Jacques Parienti| Miet Schetz
Editorial
Volume 44, Issue 7 / July , 2018

Pages 1156 - 1158

No abstract available.

References

  1. Gaudry S, Hajage D, Schortgen F, Martin-Lefevre L, Pons B, Boulet E, Boyer A, Chevrel G, Lerolle N, Carpentier D, de Prost N, Lautrette A, Bretagnol A, Mayaux J, Nseir S, Megarbane B, Thirion M, Forel JM, Maizel J, Yonis H, Markowicz P, Thiery G, Tubach F, Ricard JD, Dreyfuss D, AKIKI Study Group (2016) Initiation strategies for renal-replacement therapy in the intensive care unit. N Engl J Med 375:122–133
    • View reference on publisher's website
    • View reference on PubMed
  2. Zarbock A, Kellum JA, Schmidt C, Van Aken H, Wempe C, Pavenstädt H, Boanta A, Gerß J, Meersch M (2016) Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: The ELAIN randomized clinical trial. JAMA 315:2190–2199
    • View reference on publisher's website
    • View reference on PubMed
  3. Bagshaw SM, Lamontagne F, Joannidis M, Wald R (2016) When to start renal replacement therapy in critically ill patients with acute kidney injury: comment on AKIKI and ELAIN. Crit Care 20:245. https://doi.org/10.1186/s13054-016-1424-0
    • View reference on publisher's website
    • View reference on PubMed
  4. Klein SJ, Brandtner AK, Ulmer H et al (2018) Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis. Intensive Care Med 44(3):323–336. https://doi.org/10.1007/s00134-018-5126-8
  5. Cook NR (2007) Use and misuse of the receiver operating characteristic curve in risk prediction. Circulation 115:928–935. https://doi.org/10.1161/CIRCULATIONAHA.106.672402
    • View reference on publisher's website
    • View reference on PubMed
  6. Gail MH, Pfeiffer RM (2005) On criteria for evaluating models of absolute risk. Biostatistics 6:227–239. https://doi.org/10.1093/biostatistics/kxi005
    • View reference on publisher's website
    • View reference on PubMed
  7. Diamond GA (1992) What price perfection? Calibration and discrimination of clinical prediction models. J Clin Epidemiol 45:85–89. https://doi.org/10.1016/0895-4356(92)90192-P
    • View reference on publisher's website
    • View reference on PubMed
  8. Prowle JR (2015) Measurement of AKI biomarkers in the ICU: still striving for appropriate clinical indications. Intensive Care Med 41:541–543. https://doi.org/10.1007/s00134-015-3662-z
  9. Prowle JR, Schetz M (2017) Validating benefit of biomarker-directed therapy for acute kidney injury: can you have your cake and eat it? Intensive Care Med 43:578–580. https://doi.org/10.1007/s00134-017-4710-7
  10. Meersch M, Schmidt C, Hoffmeier A et al (2017) Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial. Intensive Care Med 43:1551–1561. https://doi.org/10.1007/s00134-016-4670-3
  11. Wong HR, Lindsell CJ, Pettilä V et al (2014) A multibiomarker-based outcome risk stratification model for adult septic shock. Crit Care Med 42:781–789. https://doi.org/10.1097/CCM.0000000000000106
    • View reference on publisher's website
    • View reference on PubMed
  12. Cohen J, Guyatt G, Bernard GR et al (2001) New strategies for clinical trials in patients with sepsis and septic shock. Crit Care Med 29:880–886
    • View reference on publisher's website
    • View reference on PubMed
  13. Marshall JC (2008) Sepsis: rethinking the approach to clinical research. J Leukoc Biol 83:471–482. https://doi.org/10.1189/jlb.0607380
    • View reference on publisher's website
    • View reference on PubMed
  14. Hosmer DW, Hosmer T, Le Cessie S, Lemeshow S (1997) A comparison of goodness-of-fit tests for the logistic regression model. Stat Med 16:965–980
    • View reference on publisher's website
    • View reference on PubMed

Sign In

Connect with ICM

Top 5 Articles Editors Picks Supplement