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The clinical features of cardiac involvement in patients with severe thrombotic thrombocytopenic purpura

Aude-Marie Fourmont| Lara Zafrani| Eric Mariotte| Lionel Galicier| Bérangère Joly| Sybille Merceron| Rémi Bertinchamp| Virginie Lemiale| Audrey de Jong| Sandrine Valade| Michael Darmon| Agnès Veyradier| Elie Azoulay
Volume 44, Issue 6 / June , 2018

Pages 963 - 965

No abstract available.


  1. Mariotte E, Azoulay E, Galicier L et al (2016) Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy. Lancet Haematol 3:e237–245. https://doi.org/10.1016/S2352-3026(16)30018-7
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  2. Mannucci PM (2015) Understanding organ dysfunction in thrombotic thrombocytopenic purpura. Intensive Care Med 41:715–718. https://doi.org/10.1007/s00134-014-3630-z
  3. Benhamou Y, Boelle P-Y, Baudin B et al (2015) Cardiac troponin-I on diagnosis predicts early death and refractoriness in acquired thrombotic thrombocytopenic purpura. Experience of the French Thrombotic Microangiopathies Reference Center. J Thromb Haemost 13:293–302. https://doi.org/10.1111/jth.12790
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  4. Sane DC, Streer NP, Owen J (2009) Myocardial necrosis in patients with thrombotic thrombocytopenic purpura: pathophysiology and rationale for specific therapy. Eur J Haematol 82:83–92. https://doi.org/10.1111/j.1600-0609.2008.01172.x
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  5. Mariotte E, Blet A, Galicier L et al (2013) Unresponsive thrombotic thrombocytopenic purpura in critically ill adults. Intensive Care Med 39:1272–1281. https://doi.org/10.1007/s00134-013-2873-4

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