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New blood for old? High quality evidence that fresh red blood cells confer no benefit for critically ill patients

Timothy S. Walsh| Nicole P. Juffermans
Editorial
Volume 44, Issue 4 / April , 2018

Pages 506 - 508

No abstract available.

References

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  3. Dumont LJ, AuBuchon JP (2008) Evaluation of proposed FDA criteria for the evaluation of radiolabeled red cell recovery trials. Transfusion 48:1053–1060
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  5. Muszynski JA, Bale J, Nateri J, Nicol K, Wang Y, Wright V, Marsh CB, Gavrilin MA, Sarkar A, Wewers MD, Hall MW (2015) Supernatants from stored red blood cell (RBC) units, but not RBC-derived microvesicles, suppress monocyte function in vitro. Transfusion 55(8):1937–1945
  6. Tinmouth A, Fergusson D, Yee IC, Hebert PC (2006) Clinical consequences of red cell storage in the critically ill. Transfusion 46:2014–2027
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  7. Chasse M, Fergusson DA (2017) Blood donor characteristics on transfusion outcomes-should obesity be assessed in future clinical trials?—reply. JAMA Intern Med 177:599–600
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  8. Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP (2016) Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells. Vox Sang 111:22–32
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  9. Rygard SL, Jonsson AB, Madsen MB, Perner A, Holst LB, Johansson PI, Wetterslev J (2018) Effects of shorter versus longer storage time of transfused red blood cells in adult ICU patients: a systematic review with meta-analysis and trial sequential analysis. Intensive Care Med 44(2):204–217
  10. Heddle NM, Arnold DM, Acker JP, Liu Y, Barty RL, Eikelboom JW, Webert KE, Hsia CC, O’Brien SF, Cook RJ (2016) Red blood cell processing methods and in-hospital mortality: a transfusion registry cohort study. Lancet Haematol 3:e246–e254
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