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Decreased susceptibility to chlorhexidine affects a quarter of Escherichia coli isolates responsible for pneumonia in ICU patients

Béatrice La Combe| Alexandre Bleibtreu| Jonathan Messika| Romain Fernandes| Olivier Clermont| Catherine Branger| Typhaine Billard-Pomares| Guilène Barnaud| Fatma Magdoud| Matthieu Eveillard| Achille Kouatchet| Sigismond Lasocki| Pierre Asfar| Stéphane Corvec| Karim Lakhal| Laurence Armand-Lefevre| Michel Wolff| Jean-François Timsit| Sandrine Bourdon| Jean Reignier| Stéphanie Martin| Vincent Fihman
Letter
Volume 44, Issue 4 / April , 2018

Pages 531 - 533

No abstract available.

References

  1. Klompas M, Speck K, Howell MD et al (2014) Reappraisal of routine oral care with chlorhexidine gluconate for patients receiving mechanical ventilation: systematic review and meta-analysis. JAMA Intern Med 174:751–761. https://doi.org/10.1001/jamainternmed.2014.359
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  2. Kollef MH, Ricard J-D, Roux D et al (2017) A randomized trial of the amikacin fosfomycin inhalation system for the adjunctive therapy of gram-negative ventilator-associated pneumonia: IASIS trial. Chest 151:1239–1246. https://doi.org/10.1016/j.chest.2016.11.026
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  3. McNeil JC, Kok EY, Vallejo JG et al (2015) Clinical and molecular features of decreased chlorhexidine susceptibility among nosocomial staphylococcus aureus isolates at Texas children’s hospital. Antimicrob Agents Chemother 60:1121–1128. https://doi.org/10.1128/AAC.02011-15
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  4. Dufour N, Clermont O, La Combe B et al (2016) Bacteriophage LM33_P1, a fast-acting weapon against the pandemic ST131-O25b:H4 Escherichia coli clonal complex. J Antimicrob Chemother 71:3072–3080. https://doi.org/10.1093/jac/dkw253
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  5. Musteata FM, Pawliszyn J (2005) Assay of stability, free and total concentration of chlorhexidine in saliva by solid phase microextraction. J Pharm Biomed Anal 37:1015–1024. https://doi.org/10.1016/j.jpba.2004.09.055
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