Log in | Register

Real -time PCR for early microbiological diagnosis: is it time?

José-Artur Paiva| Kevin B. Laupland
Editorial
Volume 43, Issue 11 / November , 2017

Pages 1714 - 1716

No abstract available.

References

  1. Buehler S, Madison B, Snyder S, Derzon J et al (2016) Effectiveness of practices to increase timeliness of providing targeted therapy for inpatients with bloodstream infections: a laboratory medicine best practices systematic review and meta-analysis. Clin Microbiol Rev 29:59–103
    • View reference on publisher's website
    • View reference on PubMed
  2. Huang AM, Newton D, Kunapuli A, Gandhi TN et al (2013) Impact of rapid organism identification via matrix-assisted laser desorption/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemia. Clin Infect Dis 57:1237–1245
    • View reference on publisher's website
    • View reference on PubMed
  3. Malcolmson C, Ng K, Hughes S, Kissoon N et al (2016) Impact of Matrix-Assisted Laser Desorption and Ionization Time-of-Flight and Antimicrobial Stewardship Intervention on Treatment of Bloodstream Infections in Hospitalized Children. J Pediatric Infect Dis Soc. doi:10.1093/jpids/piw033
  4. Jung JS, Popp C, Sparbier K, Lange C, Kostrzewa M, Schubert S (2014) Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for rapid detection of β-lactam resistance in Enterobacteriaceae derived from blood cultures. J Clin Microbiol 52(3):924–930. doi:10.1128/JCM.02691-13
    • View reference on publisher's website
    • View reference on PubMed
  5. Cillóniz C, Torres A, Niederman M, van der Eerden M et al (2016) Community-acquired pneumonia related to intracellular pathogens. Intensive Care Med 42:1374–1386. doi:10.1007/s00134-016-4394-4
  6. Papazian L, Calfee CS, Chiumello D, Luyt CE et al (2016) Diagnostic workup for ARDS patients. Intensive Care Med 42:674–685. doi:10.1007/s00134-016-4324-5
  7. Sircar M, Ranjan P, Gupta R, Jha OK et al (2016) Impact of bronchoalveolar lavage multiplex polymerase chain reaction on microbiological yield and therapeutic decisions in severe pneumonia in intensive care unit. J Crit Care 31:227–232
    • View reference on publisher's website
    • View reference on PubMed
  8. Warhurst G, Maddi S, Dunn G, Ghrew M et al (2015) Diagnostic accuracy of SeptiFast multi-pathogen real-time PCR in the setting of suspected healthcare-associated bloodstream infection. Intensive Care Med 41:86–93
  9. Dark P, Blackwood B, Gates S, McAuley D et al (2015) Accuracy of LightCycler SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis. Intensive Care Med 41:21–33
  10. Cambau E, Bauer M (2015) Multi-pathogen real-time PCR system adds benefit for my patients: yes. Intensive Care Med 41:528–530
  11. Vincent JL, Brealey D, Libert N, Abidi NE et al (2015) Rapid diagnosis of infection in the critically ill, a multicenter study of molecular detection in bloodstream infections, pneumonia, and sterile site infections. Crit Care Med 43:2283–2291
    • View reference on publisher's website
    • View reference on PubMed
  12. Banerjee R, Teng CB, Cunningham SA, Ihde SM et al (2015) Randomized trial of rapid multiplex polymerase chain reaction-based blood culture identification and susceptibility testing. Clin Infect Dis 61(7):1071–1080
    • View reference on publisher's website
    • View reference on PubMed
  13. Cambau E, Durand-Zaleski I, Bretagne S, Brun-Buisson C et al (2017) Performance and economic evaluation of the molecular detection of pathogens for patients with severe infections: the EVAMICA open-label cluster-randomised interventional crossover trial. Intensive Care Med. doi:10.1007/s00134-017-4766-4
    • View reference on PubMed

Sign In

Connect with ICM

Top 5 Articles Editors Picks Supplement