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Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient–ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellaneaOpen access

Massimo Antonelli| Marc Bonten| Maurizio Cecconi| Jean Chastre| Giuseppe Citerio| Giorgio Conti| J. R. Curtis| Goran Hedenstierna| Michael Joannidis| Duncan Macrae| Salvatore M. Maggiore| Jordi Mancebo| Alexandre Mebazaa| Jean-Charles Preiser| Patricia Rocco| Jean-François Timsit| Jan Wernerman| Haibo Zhang
Year in Review 2012
Volume 39, Issue 4 / April , 2013

Pages 543 - 557

No abstract available.


  1. Carrillo A, Gonzalez-Diaz G, Ferrer M, Martinez-Quintana ME, Lopez-Martinez A, Llamas N, Alcazar M, Torres A (2012) Non-invasive ventilation in community-acquired pneumonia and severe acute respiratory failure. Intensive Care Med 38:458–466
  2. Piquilloud L, Tassaux D, Bialais E, Lambermont B, Sottiaux T, Roeseler J, Laterre PF, Jolliet P, Revelly JP (2012) Neurally adjusted ventilatory assist (NAVA) improves patient-ventilator interaction during non-invasive ventilation delivered by face mask. Intensive Care Med 38:1624–1631
  3. Vaschetto R, Turucz E, Dellapiazza F, Guido S, Colombo D, Cammarota G, Della Corte F, Antonelli M, Navalesi P (2012) Noninvasive ventilation after early extubation in patients recovering from hypoxemic acute respiratory failure: a single-centre feasibility study. Intensive Care Med 38:1599–1606
  4. Laghi F, Fernandez R (2012) Noninvasive ventilation for weaning in hypoxemic respiratory failure: not ready for prime time. Intensive Care Med 38:1583–1585
  5. Ramirez A, Delord V, Khirani S, Leroux K, Cassier S, Kadlub N, Aubertin G, Picard A, Fauroux B (2012) Interfaces for long-term noninvasive positive pressure ventilation in children. Intensive Care Med 38:655–662
  6. Olivieri C, Costa R, Conti G, Navalesi P (2012) Bench studies evaluating devices for non-invasive ventilation: critical analysis and future perspectives. Intensive Care Med 38:160–167
  7. Ouanes-Besbes L, Dachraoui F, Ouanes I, Bouneb R, Jalloul F, Dlala M, Najjar MF, Abroug F (2012) NT-proBNP levels at spontaneous breathing trial help in the prediction of post-extubation respiratory distress. Intensive Care Med 38:788–795
  8. Vivier E, Mekontso Dessap A, Dimassi S, Vargas F, Lyazidi A, Thille AW, Brochard L (2012) Diaphragm ultrasonography to estimate the work of breathing during non-invasive ventilation. Intensive Care Med 38:796–803
  9. Banner MJ, Euliano NR, Martin AD, Al-Rawas N, Layon AJ, Gabrielli A (2012) Noninvasive work of breathing improves prediction of post-extubation outcome. Intensive Care Med 38:248–255
  10. Blanch L, Sales B, Montanya J, Lucangelo U, Garcia-Esquirol O, Villagra A, Chacon E, Estruga A, Borelli M, Burgueno MJ, Oliva JC, Fernandez R, Villar J, Kacmarek R, Murias G (2012) Validation of the Better Care® system to detect ineffective efforts during expiration in mechanically ventilated patients: a pilot study. Intensive Care Med 38:772–780
  11. Georgopoulos D (2012) Ineffective efforts during mechanical ventilation: the brain wants, the machine declines. Intensive Care Med 38:738–740
  12. Arnal JM, Wysocki M, Novotni D, Demory D, Lopez R, Donati S, Granier I, Corno G, Durand-Gasselin J (2012) Safety and efficacy of a fully closed-loop control ventilation (IntelliVent-ASV®) in sedated ICU patients with acute respiratory failure: a prospective randomized crossover study. Intensive Care Med 38:781–787
  13. Prigent H, Lejaille M, Terzi N, Annane D, Figere M, Orlikowski D, Lofaso F (2012) Effect of a tracheostomy speaking valve on breathing-swallowing interaction. Intensive Care Med 38(1):85–90. doi:10.1007/s00134-011-2417-8
  14. Leonhardt S, Lachmann B (2012) Electrical impedance tomography: the holy grail of ventilation and perfusion monitoring? Intensive Care Med 38:1917–1929
  15. Patroniti N, Bellani G, Saccavino E, Zanella A, Grasselli G, Isgro S, Milan M, Foti G, Pesenti A (2012) Respiratory pattern during neurally adjusted ventilatory assist in acute respiratory failure patients. Intensive Care Med 38:230–239
  16. de la Oliva P, Schuffelmann C, Gomez-Zamora A, Villar J, Kacmarek RM (2012) Asynchrony, neural drive, ventilatory variability and COMFORT: NAVA versus pressure support in pediatric patients. A non-randomized cross-over trial. Intensive Care Med 38:838–846
  17. Fine-Goulden MR, Puppala NK, Durward A (2012) Mechanisms of ventilator dependence in children with neuromuscular and respiratory control disorders identified by monitoring diaphragm electrical activity. Intensive Care Med 38:2072–2079
  18. Sinha P, Soni N (2012) Comparison of volumetric capnography and mixed expired gas methods to calculate physiological dead space in mechanically ventilated ICU patients. Intensive Care Med 38:1712–1717
  19. Eastwood G, Bellomo R, Bailey M, Taori G, Pilcher D, Young P, Beasley R (2012) Arterial oxygen tension and mortality in mechanically ventilated patients. Intensive Care Med 38:91–98
  20. Nesseler N, Frenel JV, Launey Y, Morcet J, Malledant Y, Seguin P (2012) Pulse oximetry and high-dose vasopressors: a comparison between forehead reflectance and finger transmission sensors. Intensive Care Med 38:1718–1722
  21. Kondili E, Alexopoulou C, Xirouchaki N, Georgopoulos D (2012) Effects of propofol on sleep quality in mechanically ventilated critically ill patients: a physiological study. Intensive Care Med 38:1640–1646
  22. Ferguson ND, Fan E, Camporota L, Antonelli M, Anzueto A, Beale R, Brochard L, Brower R, Esteban A, Gattinoni L, Rhodes A, Slutsky AS, Vincent JL, Rubenfeld GD, Thompson BT, Ranieri VM (2012) The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med 38:1573–1582
  23. Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS (2012) Acute respiratory distress syndrome: the Berlin definition. JAMA 307:2526–2533
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  24. Gonzalez-Lopez A, Garcia-Prieto E, Batalla-Solis E, Amado-Rodriguez L, Avello N, Blanch L, Albaiceta GM (2012) Lung strain and biological response in mechanically ventilated patients. Intensive Care Med 38:240–247
  25. Guo WA, Knight PR, Raghavendran K (2012) The receptor for advanced glycation end products and acute lung injury/acute respiratory distress syndrome. Intensive Care Med 38:1588–1598
  26. Chiumello D, Taccone P, Berto V, Marino A, Migliara G, Lazzerini M, Gattinoni L (2012) Long-term outcomes in survivors of acute respiratory distress syndrome ventilated in supine or prone position. Intensive Care Med 38:221–229
  27. Cox CE, Porter LS, Hough CL, White DB, Kahn JM, Carson SS, Tulsky JA, Keefe FJ (2012) Development and preliminary evaluation of a telephone-based coping skills training intervention for survivors of acute lung injury and their informal caregivers. Intensive Care Med 38:1289–1297
  28. Grasso S, Terragni P, Birocco A, Urbino R, Del Sorbo L, Filippini C, Mascia L, Pesenti A, Zangrillo A, Gattinoni L, Ranieri VM (2012) ECMO criteria for influenza A (H1N1)-associated ARDS: role of transpulmonary pressure. Intensive Care Med 38:395–403
  29. Richard JC, Marini JJ (2012) Transpulmonary pressure as a surrogate of plateau pressure for lung protective strategy: not perfect but more physiologic. Intensive Care Med 38:339–341
  30. Korver EP, Ganushchak YM, Simons AP, Donker DW, Maessen JG, Weerwind PW (2012) Quantification of recirculation as an adjuvant to transthoracic echocardiography for optimization of dual-lumen extracorporeal life support. Intensive Care Med 38:906–909
  31. MacLaren G, Combes A, Bartlett RH (2012) Contemporary extracorporeal membrane oxygenation for adult respiratory failure: life support in the new era. Intensive Care Med 38:210–220
  32. Morris AH (2012) Exciting new ECMO technology awaits compelling scientific evidence for widespread use in adults with respiratory failure. Intensive Care Med 38:186–188
  33. Kluge S, Braune SA, Engel M, Nierhaus A, Frings D, Ebelt H, Uhrig A, Metschke M, Wegscheider K, Suttorp N, Rousseau S (2012) Avoiding invasive mechanical ventilation by extracorporeal carbon dioxide removal in patients failing noninvasive ventilation. Intensive Care Med 38:1632–1639
  34. Gottlieb J, Warnecke G, Hadem J, Dierich M, Wiesner O, Fuhner T, Strueber M, Haverich A, Welte T (2012) Outcome of critically ill lung transplant candidates on invasive respiratory support. Intensive Care Med 38:968–975
  35. Oto J, Yamamoto K, Koike S, Onodera M, Imanaka H, Nishimura M (2012) Sleep quality of mechanically ventilated patients sedated with dexmedetomidine. Intensive Care Med 38:1982–1989
  36. Burbano NH, Otero AV, Berry DE, Orr RA, Munoz RA (2012) Discontinuation of prolonged infusions of dexmedetomidine in critically ill children with heart disease. Intensive Care Med 38:300–307
  37. Duman N, Tuzun F, Sutcuoglu S, Yesilirmak CD, Kumral A, Ozkan H (2012) Impact of volume guarantee on synchronized ventilation in preterm infants: a randomized controlled trial. Intensive Care Med 38:1358–1364
  38. Bhatia R, Schmolzer GM, Davis PG, Tingay DG (2012) Electrical impedance tomography can rapidly detect small pneumothoraces in surfactant-depleted piglets. Intensive Care Med 38:308–315
  39. Miedema M, de Jongh FH, Frerichs I, van Veenendaal MB, van Kaam AH (2012) Regional respiratory time constants during lung recruitment in high-frequency oscillatory ventilated preterm infants. Intensive Care Med 38:294–299
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  43. da Silva PS, Fonseca MC, Iglesias SB, Junior EL, de Aguiar VE, de Carvalho WB (2012) Nebulized 0.5, 2.5 and 5 ml l-epinephrine for post-extubation stridor in children: a prospective, randomized, double-blind clinical trial. Intensive Care Med 38:286–293
  44. Ganu SS, Gautam A, Wilkins B, Egan J (2012) Increase in use of non-invasive ventilation for infants with severe bronchiolitis is associated with decline in intubation rates over a decade. Intensive Care Med 38:1177–1183
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  46. Smalley N, MacLaren G, Best D, Paul E, Butt W (2012) Outcomes in children with refractory pneumonia supported with extracorporeal membrane oxygenation. Intensive Care Med 38:1001–1007
  47. Paulides FM, Plotz FB, Verweij-van den Oudenrijn LP, van Gestel JP, Kampelmacher MJ (2012) Thirty years of home mechanical ventilation in children: escalating need for pediatric intensive care beds. Intensive Care Med 38:847–852
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  49. Algra SO, Driessen MM, Schadenberg AW, Schouten AN, Haas F, Bollen CW, Houben ML, Jansen NJ (2012) Bedside prediction rule for infections after pediatric cardiac surgery. Intensive Care Med 38:474–481
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  53. Davidson J, Tong S, Hancock H, Hauck A, da Cruz E, Kaufman J (2012) Prospective validation of the vasoactive-inotropic score and correlation to short-term outcomes in neonates and infants after cardiothoracic surgery. Intensive Care Med 38:1184–1190
  54. Ricci Z, Garisto C, Favia I, Vitale V, Di Chiara L, Cogo PE (2012) Levosimendan infusion in newborns after corrective surgery for congenital heart disease: randomized controlled trial. Intensive Care Med 38:1198–1204
  55. Hassinger AB, Wainwright MS, Lane JC, Haymond S, Backer CL, Wald E (2012) Elevated preoperative serum asymmetrical dimethylarginine (ADMA) is associated with poor outcomes after pediatric cardiac surgery. Intensive Care Med 38:1697–1704
  56. Mastropietro CW, Mahan M, Valentine KM, Clark JA, Hines PC, Walters HL 3rd, Delius RE, Sarnaik AP, Rossi NF (2012) Copeptin as a marker of relative arginine vasopressin deficiency after pediatric cardiac surgery. Intensive Care Med 38:2047–2054
  57. Chakkarapani E, Thoresen M, Liu X, Walloe L, Dingley J (2012) Xenon offers stable haemodynamics independent of induced hypothermia after hypoxia-ischaemia in newborn pigs. Intensive Care Med 38:316–323
  58. Grollmuss O, Demontoux S, Capderou A, Serraf A, Belli E (2012) Electrical velocimetry as a tool for measuring cardiac output in small infants after heart surgery. Intensive Care Med 38:1032–1039
  59. Konig K, Casalaz DM, Burke EJ, Watkins A (2012) Accuracy of non-invasive blood pressure monitoring in very preterm infants. Intensive Care Med 38:670–676
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  63. Stocker M, Allen M, Pool N, De Costa K, Combes J, West N, Burmester M (2012) Impact of an embedded simulation team training programme in a paediatric intensive care unit: a prospective, single-centre, longitudinal study. Intensive Care Med 38:99–104
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  65. Martinez-Anton A, Sanchez JI, Casanueva L (2012) Impact of an intervention to reduce prescribing errors in a pediatric intensive care unit. Intensive Care Med 38:1532–1538
  66. Imamura T, Nakagawa S, Goldman RD, Fujiwara T (2012) Validation of pediatric index of mortality 2 (PIM2) in a single pediatric intensive care unit in Japan. Intensive Care Med 38:649–654
  67. Leteurtre S, Grandbastien B, Leclerc F, Parslow R (2012) International comparison of the performance of the paediatric index of mortality (PIM) 2 score in two national data sets. Intensive Care Med 38:1372–1380
  68. Morris KP, McShane P, Stickley J, Parslow RC (2012) The relationship between blood lactate concentration, the Paediatric Index of Mortality 2 (PIM2) and mortality in paediatric intensive care. Intensive Care Med 38:2042–2046
  69. Bastero-Minon P, Russell JL, Humpl T (2012) Frequency, characteristics, and outcomes of pediatric patients readmitted to the cardiac critical care unit. Intensive Care Med 38:1352–1357
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  71. Colville G, Pierce C (2012) Patterns of post-traumatic stress symptoms in families after paediatric intensive care. Intensive Care Med 38:1523–1531
  72. Shime N, Kawasaki T, Saito O, Akamine Y, Toda Y, Takeuchi M, Sugimura H, Sakurai Y, Iijima M, Ueta I, Shimizu N, Nakagawa S (2012) Incidence and risk factors for mortality in paediatric severe sepsis: results from the national paediatric intensive care registry in Japan. Intensive Care Med 38:1191–1197
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  74. Gatterre P, Oualha M, Dupic L, Iserin F, Bodemer C, Lesage F, Hubert P (2012) Kawasaki disease: an unexpected etiology of shock and multiple organ dysfunction syndrome. Intensive Care Med 38:872–878
  75. Paize F, Sarginson R, Makwana N, Baines PB, Thomson AP, Sinha I, Hart CA, Riordan A, Hawkins KC, Carrol ED, Parry CM (2012) Changes in the sublingual microcirculation and endothelial adhesion molecules during the course of severe meningococcal disease treated in the paediatric intensive care unit. Intensive Care Med 38:863–871
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  77. Lombel RM, Kommareddi M, Mottes T, Selewski DT, Han YY, Gipson DS, Collins KL, Heung M (2012) Implications of different fluid overload definitions in pediatric stem cell transplant patients requiring continuous renal replacement therapy. Intensive Care Med 38:663–669
  78. Kirkham FJ, Wade AM, McElduff F, Boyd SG, Tasker RC, Edwards M, Neville BG, Peshu N, Newton CR (2012) Seizures in 204 comatose children: incidence and outcome. Intensive Care Med 38:853–862
  79. Gunn JK, Beca J, Hunt RW, Olischar M, Shekerdemian LS (2012) Perioperative amplitude-integrated EEG and neurodevelopment in infants with congenital heart disease. Intensive Care Med 38:1539–1547
  80. Welzing L, Oberthuer A, Junghaenel S, Harnischmacher U, Stutzer H, Roth B (2012) Remifentanil/midazolam versus fentanyl/midazolam for analgesia and sedation of mechanically ventilated neonates and young infants: a randomized controlled trial. Intensive Care Med 38:1017–1024
  81. Silver G, Traube C, Kearney J, Kelly D, Yoon MJ, Nash Moyal W, Gangopadhyay M, Shao H, Ward MJ (2012) Detecting pediatric delirium: development of a rapid observational assessment tool. Intensive Care Med 38:1025–1031
  82. Karaguzel G, Atay S, Deger O, Imamoglu M, Okten A (2012) The effects of three specific conditions related to critical care on adrenal function in children. Intensive Care Med 38:1689–1696
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  84. Rippel C, South M, Butt WW, Shekerdemian LS (2012) Vitamin D status in critically ill children. Intensive Care Med 38:2055–2062
  85. Plumb JO, Morris CG (2012) Clinical review: spinal imaging for the adult obtunded blunt trauma patient: update from 2004. Intensive Care Med 38:752–771
  86. Zhang Z, Hongying N (2012) Efficacy and safety of regional citrate anticoagulation in critically ill patients undergoing continuous renal replacement therapy. Intensive Care Med 38:20–28
  87. Brotschi B, Grass B, Weiss M, Doell C, Bernet V (2012) In-line filter included into the syringe infusion pump assembly reduces flow irregularities. Intensive Care Med 38:518–522
  88. Mallat J, Barrailler S, Lemyze M, Benzidi Y, Pepy F, Gasan G, Tronchon L, Thevenin D (2012) The repeatability of Stewart’s parameters and anion gap in a cohort of critically ill adult patients. Intensive Care Med 38:2026–2031
  89. Soh CR, Pietrobon R, Freiberger JJ, Chew ST, Rajgor D, Gandhi M, Shah J, Moon RE (2012) Hyperbaric oxygen therapy in necrotising soft tissue infections: a study of patients in the United States Nationwide Inpatient Sample. Intensive Care Med 38:1143–1151
  90. Lefebvre JC, Lyazidi A, Parceiro M, Sferrazza Papa GF, Akoumianaki E, Pugin D, Tassaux D, Brochard L, Richard JC (2012) Bench testing of a new hyperbaric chamber ventilator at different atmospheric pressures. Intensive Care Med 38:1400–1404

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