• View Full Article
• View Full Article PDF
• Download Citation

– Lung hyperinflation – Acute respiratory failure – Mechanical ventilation – Lung volume measurements – Computed tomography

References

1. Mull RT (1984) Mass estimates by computed tomography: physical density from CT numbers. AJR Am J Roentgenol 143:1101–1104
   
   • 
2. Dos Santos CC, Slutsky AS (2000) Invited review: mechanisms of ventilator-induced lung injury: a perspective. J Appl Physiol 89:1645–1655
   
   • 
3. Dambrosio M, Roupie E, Mollet JJ, Anglade MC, Vasile N, Lemaire F, Brochard L (1997) Effects of positive end-expiratory pressure and different tidal volumes on alveolar recruitment and hyperinflation. Anesthesiology 87:495–503
   
   • 
   • 
4. Vieira SR, Puybasset L, Richecoeur J, Lu Q, Cluzel P, Gusman PB, Coriat P, Rouby JJ (1998) A lung computed tomographic assessment of positive end-expiratory pressure-induced lung overdistension. Am J Respir Crit Care Med 158:1571–1577
   
   • 
5. Vieira SR, Nieszkowska A, Lu Q, Elman M, Sartorius A, Rouby JJ (2005) Low spatial resolution computed tomography underestimates lung overinflation resulting from positive pressure ventilation. Crit Care Med 33:741–749
   
   • 
   • 
6. David M, Karmrodt J, Bletz C, David S, Herweling A, Kauczor HU, Markstaller K (2005) Analysis of atelectasis, ventilated, and hyperinflated lung during mechanical ventilation by dynamic CT. Chest 128:3757–3770
   
   • 
   • 
7. Terragni PP, Rosboch G, Tealdi A, Corno E, Menaldo E, Davini O, Gandini G, Herrmann P, Mascia L, Quintel M, Slutsky AS, Gattinoni L, Ranieri VM (2007) Tidal hyperinflation during low tidal volume ventilation in acute respiratory distress syndrome. Am J Respir Crit Care Med 175:160–166
   
   • 
   • 
8. Schreiter D, Reske A, Stichert B, Seiwerts M, Bohm SH, Kloeppel R, Josten C (2004) Alveolar recruitment in combination with sufficient positive end-expiratory pressure increases oxygenation and lung aeration in patients with severe chest trauma. Crit Care Med 32:968–975
   
   • 
   • 
9. Carvalho AR, Jandre FC, Pino AV, Bozza FA, Saluh JI, Rodrigues R, Soares JH, Giannella-Neto A (2006) Effects of descending positive end-expiratory pressure on lung mechanics and aeration in healthy anaesthetized piglets. Crit Care 10:R122
   
   • 
   • 
10. Malbouisson LM, Muller JC, Constantin JM, Lu Q, Puybasset L, Rouby JJ, CT Scan ARDS Study Group (2001) Computed tomography assessment of positive end-expiratory pressure-induced alveolar recruitment in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 163:1444–1450
    
    • 
11. Suarez-Sipmann F, Bohm SH, Tusman G, Pesch T, Thamm O, Reissmann H, Reske A, Magnusson A, Hedenstierna G (2007) Use of dynamic compliance for open lung positive end-expiratory pressure titration in an experimental study. Crit Care Med 35:214–221
    
    • 
    • 
12. Borges JB, Okamoto VN, Matos GFJ, Caramez MPR, Arantes PR, Barros F, Souza CE, Victorino JA, Kacmarek RM, Barbas CSV, Carvalho CRR, Amato MBP (2006) Reversibility of lung collapse and hypoxemia in early acute respiratory distress syndrome. Am J Respir Crit Care Med 174:268–278
    
    • 
    • 
13. Gattinoni L, Caironi P, Cressoni M, Chiumello D, Ranieri VM, Quintel M, Russo S, Patroniti N, Cornejo R, Bugedo G (2006) Lung recruitment in patients with the acute respiratory distress syndrome. N Engl J Med 354:1775–1786
    
    • 
    • 
14. Gattinoni L, Caironi P, Pelosi P, Goodman LR (2001) What has computed tomography taught us about the acute respiratory distress syndrome? Am J Respir Crit Care Med 164:1701–1711
    
    • 
15. Albaiceta GM, Taboada F, Parra D, Luyando LH, Calvo J, Menendez R, Otero J (2004) Tomographic study of the inflection points of the pressure–volume curve in acute lung injury. Am J Respir Crit Care Med 170:1066–1072
    
    • 
    • 
16. Madani A, Keyzer C, Gevenois PA (2001) Quantitative computed tomography assessment of lung structure and function in pulmonary emphysema. Eur Respir J 18:720–730
    
    • 
    • 
17. Madani A, Keyzer C, Gevenois PA (2004) Computed tomography assessment of lung structure and function in pulmonary emphysema. Eur Respir Mon 30:145–160
18. Madani A, Zanen J, de Maertelaer V, Gevenois PA (2006) Pulmonary emphysema: objective quantification at multi-detector row CT—comparison with macroscopic and microscopic morphometry. Radiology 238:1036–1043
    
    • 
    • 
19. Stoel BC, Stolk J (2004) Optimization and standardization of lung densitometry in the assessment of pulmonary emphysema. Invest Radiol 39:681–688
    
    • 
    • 
20. Kemerink GJ, Kruize HH, Lamers RJ (1997) The CT’s sample volume as an approximate, instrumental measure for density resolution in densitometry of the lung. Med Phys 24:1615–1620
    
    • 
    • 
21. Kemerink GJ, Kruize HH, Lamers RJ, van Engelshoven JM (1997) CT lung densitometry: dependence of CT number histograms on sample volume and consequences for scan protocol comparability. J Comput Assist Tomogr 21:948–954
    
    • 
    • 
22. Boedeker KL, McNitt-Gray MF, Rogers SR, Truong DA, Brown MS, Gjertson DW, Goldin JG (2004) Emphysema: effect of reconstruction algorithm on CT imaging measures. Radiology 232:295–301
    
    • 
    • 
23. Shaker SB, Dirksen A, Laursen LC, Maltbaek N, Christensen L, Sander U, Seersholm N, Skovgaard LT, Nielsen L, Kok-Jensen A (2004) Short-term reproducibility of computed tomography-based lung density measurements in alpha-1 antitrypsin deficiency and smokers with emphysema. Acta Radiol 45:424–430
    
    • 
    • 
24. Parr DG, Stoel BC, Stolk J, Nightingale PG, Stockley RA (2004) Influence of calibration on densitometric studies of emphysema progression using computed tomography. Am J Respir Crit Care Med 170:883–890
    
    • 
    • 
25. Newell JD Jr, Hogg JC, Snider GL (2004) Report of a workshop: quantitative computed tomography scanning in longitudinal studies of emphysema. Eur Respir J 23:769–775
    
    • 
    • 
26. Stoel BC, Bakker ME, Stolk J, Dirksen A, Stockley RA, Piitulainen E, Russi EW, Reiber JH (2004) Comparison of the sensitivities of 5 different computed tomography scanners for the assessment of the progression of pulmonary emphysema: a phantom study. Invest Radiol 39:1–7
    
    • 
    • 
27. Müller NL, Coxson H (2002) Chronic obstructive pulmonary disease. 4: imaging the lungs in patients with chronic obstructive pulmonary disease. Thorax 57:982–985
    
    • 
    • 
28. Hoffman EA, Reinhardt JM, Sonka M, Simon BA, Guo J, Saba O, Chon D, Samrah S, Shikata H, Tschirren J, Palagyi K, Beck KC, McLennan G (2003) Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and function. Acad Radiol 10:1104–1118
    
    • 
    • 
29. Hoffman EA, Olson LE (1998) Characteristics of respiratory system complexity captured via X-ray computed tomography. In: Hlastala MP, Robertson HT (eds) Complexity in structure and function of the lung. Marcel Dekker, New York, pp 325–378
30. Zaporozhan J, Ley S, Weinheimer O, Eberhardt R, Tsakiris I, Noshi Y, Herth F, Kauczor HU (2006) Multi-detector CT of the chest: influence of dose onto quantitative evaluation of severe emphysema: a simulation study. J Comput Assist Tomogr 30:460–468
    
    • 
    • 
31. Zaporozhan J, Ley S, Eberhardt R, Weinheimer O, Iliyushenko S, Herth F, Kauczor HU (2005) Paired inspiratory/expiratory volumetric thin-slice CT scan for emphysema analysis: comparison of different quantitative evaluations and pulmonary function test. Chest 128:3212–3220
    
    • 
    • 
32. Madani A, De Maertelaer V, Zanen J, Gevenois PA (2007) Pulmonary emphysema: radiation dose and section thickness at multidetector CT quantification—comparison with macroscopic and microscopic morphometry. Radiology 243:250–257
    
    • 
    • 
33. Muller NL, Staples CA, Miller RR, Abboud RT (1988) “Density mask”. An objective method to quantitate emphysema using computed tomography. Chest 94:782–787
    
    • 
    • 
34. Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1(8476):307–310
    
    • 
35. Dewitte K, Fierens C, Stöckl D, Thienpont LM (2002) Application of the Bland–Altman plot for interpretation of method-comparison studies: a critical investigation of its practice. Clin Chem 48:799–801
    
    • 
36. Marsh S, Aldington S, Williams MV, Nowitz MR, Kingzett-Taylor A, Weatherall M, Shirtcliffe PM, McNaughton AA, Pritchard A, Beasley R (2007) Utility of lung density measurements in the diagnosis of emphysema. Respir Med 101:1512–1520
    
    • 
    • 
37. Litzlbauer HD, Neuhaeuser C, Moell A, Greschus S, Breithecker A, Franke FE, Kummer W, Rau WS (2006) Three-dimensional imaging and morphometric analysis of alveolar tissue from microfocal X-ray-computed to mography. Am J Physiol Lung Cell Mol Physiol 291:L535–L545
    
    • 
    • 
38. Mitsunobu F, Ashida K, Hosaki Y, Tsugeno H, Okamoto M, Nishida N, Nagata T, Takata S, Tanizaki Y (2003) Decreased computed tomographic lung density during exacerbation of asthma. Eur Respir J 22:106–112
    
    • 
    • 
39. Gevenois PA, De Vuyst P, de Maertelaer V, Zanen J, Jacobovitz D, Cosio MG, Yernault JC (1996) Comparison of computed density and microscopic morphometry in pulmonary emphysema. Am J Respir Crit Care Med 154:187–192
    
    • 
40. Tusman G, Suarez-Sipmann F, Böhm SH, Pech T, Reissmann H, Meschino G, Scandurra A, Hedenstierna G (2006) Monitoring dead space during recruitment and PEEP titration in an experimental model. Intensive Care Med 32:1863–1871
    
    • 
    • View ICM abstract
41. Grasso S, Stripoli T, De Michele M, Bruno F, Moschetta M, Angelelli G, Munno I, Ruggiero V, Anaclerio R, Cafarelli A, Driessen B, Fiore T (2007) ARDSnet ventilatory protocol and alveolar hyperinflation: role of positive end-expiratory pressure. Am J Respir Crit Care Med 176:761–767
    
    • 
    •