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Year in review in Intensive Care Medicine, 2006. I. Experimental studies. Clinical studies: brain injury, renal failure and endocrinologyOpen access

Peter Andrews| Elie Azoulay| Massimo Antonelli| Laurent Brochard| Christian Brun-Buisson| Daniel De Backer| Geoffrey Dobb| Jean-Yves Fagon| Herwig Gerlach| Johan Groeneveld| Duncan Macrae| Jordi Mancebo| Philipp Metnitz| Stefano Nava| Jerôme Pugin| Michael Pinsky| Peter Radermacher| Christian Richard
Year in Review 2006
Volume 33, Issue 1 / January , 2007

Pages 49 - 57

No abstract available.


  1. DiRocco JD, Pavone LA, Carney DE, Lutz CJ, Gatto LA, Landas SK, Nieman GF (2006) Dynamic alveolar mechanics in four models of lung injury. Intensive Care Med 32:140–148
  2. Schreiber T, Hueter L, Gaser E, Schmidt B, Schwarzkopf K, Rek H, Karzai W (2006) PEEP has beneficial effects on inflammation in the injured and no deleterious effects on the noninjured lung after unilateral lung acid instillation. Intensive Care Med 32:740–749
  3. Nielsen J, Nilsson M, Freden F, Hultman J, Alstrom U, Kjaergaard J, Hedenstierna G, Larsson A (2006) Central hemodynamics during lung recruitment maneuvers at hypovolemia, normovolemia and hypervolemia. A study by echocardiography and continuous pulmonary artery flow measurements in lung-injured pigs. Intensive Care Med 32:585–594
  4. Bayle F, Guerin C, Debord S, Badet M, Lemasson S, Poupelin JC, Richard JC (2006) Assessment of airway closure from deflation lung volume-pressure curve: sigmoidal equation revisited. Intensive Care Med 32:894–898
  5. Tusman G, Suarez-Sipmann F, Bohm SH, Pech T, Reissmann H, Meschino G, Scandurra A, Hedenstierna G (2006) Monitoring dead space during recruitment and PEEP titration in an experimental model. Intensive Care Med 32:1863–1871
  6. Richard JC, Le Bars D, Costes N, Bregeon F, Tourvieille C, Lavenne F, Janier M, Gimenez G, Guerin C (2006) Alveolar recruitment assessed by positron emission tomography during experimental acute lung injury. Intensive Care Med 32:1889–1894
  7. Calzia E, Radermacher P, Bein T (2006) Unveiling alveolar recruitment: the fascinating trail between theory and practice. Intensive Care Med 32:1686–1688
  8. Kolobow T, Li Bassi G, Curto F, Zanella A (2006) The Mucus Slurper: a novel tracheal tube that requires no tracheal tube suctioning. A preliminary report. Intensive Care Med 32:1414–1418
  9. Berra L, Curto F, Li Bassi G, Laquerriere P, Baccarelli A, Kolobow T (2006) Antibacterial-coated tracheal tubes cleaned with the Mucus Shaver: A novel method to retain long-term bactericidal activity of coated tracheal tubes. Intensive Care Med 32:888–893
  10. Girardi C, Tonnellier M, Goldstein I, Sartorius A, Wallet F, Rouby JJ (2006) Lung deposition of continuous and intermittent intravenous ceftazidime in experimental Pseudomonas aeruginosa bronchopneumonia. Intensive Care Med 32:2042–2048
  11. Morel DR, Frossard JL, Cikirikcioglu B, Tapponnier M, Pastor CM (2006) Time course of lung injury in rat acute pancreatitis. Intensive Care Med 32:1872–1880
  12. Thomale UW, Griebenow M, Kroppenstedt SN, Unterberg AW, Stover JF (2006) The effect of N-acetylcysteine on posttraumatic changes after controlled cortical impact in rats. Intensive Care Med 32:149–155
  13. Roesner JP, Vagts DA, Iber T, Eipel C, Vollmar B, Noldge-Schomburg GF (2006) Protective effects of PARP inhibition on liver microcirculation and function after haemorrhagic shock and resuscitation in male rats. Intensive Care Med 32:1649–1657
  14. Barth E, Radermacher P, Szabo C (2006) The world according to poly(ADP-ribose) polymerase (PARP)-update 2006. Intensive Care Med 32:1470–144
  15. Crouser ED, Julian MW, Huff JE, Mandich DV, Green-Church KB (2006) A proteomic analysis of liver mitochondria during acute endotoxemia. Intensive Care Med 32:1252–1262
  16. Giamarellos-Bourboulis EJ, Zakynthinos S, Baziaka F, Papadomichelakis E, Virtzili S, Koutoukas P, Armaganidis A, Giamarellou H, Roussos C (2006) Soluble triggering receptor expressed on myeloid cells 1 as an anti-inflammatory mediator in sepsis. Intensive Care Med 32:237–243
  17. Gibot S, Massin F (2006) Soluble form of the triggering receptor expressed on myeloid cells 1: An anti-inflammatory mediator? Intensive Care Med 32:185–187
  18. Socha LA, Gowardman J, Silva D, Correcha M, Petrosky N (2006) Elevation in interleukin 13 levels in patients diagnosed with systemic inflammatory response syndrome. Intensive Care Med 32:244–250
  19. Stanilova SA, Miteva LD, Karakolev ZT, Stefanov CS (2006) Interleukin-10–1082 promoter polymorphism in association with cytokine production and sepsis susceptibility. Intensive Care Med 32:260–266
  20. Hauser B, Kick J, Ivanyi Z, Asfar P, Ehrmann U, Muth CM, Albicini M, Wachter U, Vogt J, Bauer M, Bruckner UB, Radermacher P, Bracht H (2006) Effects of 15-deoxy-Delta(12,14)-prostaglandin-J (2) during hyperdynamic porcine endotoxemia. Intensive Care Med 32:759–765
  21. Hummler HD, Engelmann A, Pohlandt F, Hogel J, Franz AR (2006) Decreased accuracy of pulse oximetry measurements during low perfusion caused by sepsis: is the perfusion index of any value? Intensive Care Med 32:1428–1431
  22. Gehring H (2006) Pulse oximeter in a comparative test. Intensive Care Med 32:1287–9
  23. Pareznik R, Knezevic R, Voga G, Podbregar M (2006) Changes in muscle tissue oxygenation during stagnant ischemia in septic patients. Intensive Care Med 32:87–92
  24. Eikermann M, Koch G, Gerwig M, Ochterbeck C, Beiderlinden M, Koeppen S, Neuhauser M, Peters J (2006) Muscle force and fatigue in patients with sepsis and multiorgan failure. Intensive Care Med 32:251–259
  25. Wan L, Bellomo R, May CN (2006) The effect of normal saline resuscitation on vital organ blood flow in septic sheep. Intensive Care Med 32:1238–1242
  26. Knotzer H, Maier S, Dunser MW, Hasibeder WR, Hausdorfer H, Brandner J, Torgersen C, Ulmer H, Friesenecker B, Iannetti C, Pajk W (2006) Arginine vasopressin does not alter mucosal tissue oxygen tension and oxygen supply in an acute endotoxemic pig model. Intensive Care Med 32:170–174
  27. Asfar P, Radermacher P, Hauser B (2006) Vasopressin and splanchnic blood flow: vasoconstriction does not equal vasoconstriction in every organ. Intensive Care Med 32:21–23
  28. Oberbeck R, Schmitz D, Wilsenack K, Schuler M, Husain B, Schedlowski M, Exton MS (2006) Dopamine affects cellular immune functions during polymicrobial sepsis. Intensive Care Med 32:731–739
  29. Li Y, Li X, Haley M, Fitz Y, Gerstenberger E, Banks SM, Eichacker PQ, Cui X (2006) DTPA Fe(III) decreases cytokines and hypotension but worsens survival with Escherichia coli sepsis in rats. Intensive Care Med 32:1263–1270
  30. Favory R, Lancel S, Marechal X, Tissier S, Neviere R (2006) Cardiovascular protective role for activated protein C during endotoxemia in rats. Intensive Care Med 32:899–905
  31. Imperatore F, Cuzzocrea S, De Lucia D, Sessa M, Rinaldi B, Capuano A, Liguori G, Filippelli A, Rossi F (2006) Hyperbaric oxygen therapy prevents coagulation disorders in an experimental model of multiple organ failure syndrome. Intensive Care Med 32:1881–1888
  32. Oter S, Radermacher P, Matejovic M (2006) Can (hyperbaric) oxygen turn off the motor of multiorgan dysfunction? Intensive Care Med 32:1694–1696
  33. Egerod I, Christensen BV, Johansen L (2006) Trends in sedation practices in Danish intensive care units in 2003: a national survey. Intensive Care Med 32:60–66
  34. Samuelson K, Lundberg D, Fridlund B (2006) Memory in relation to depth of sedation in adult mechanically ventilated intensive care patients. Intensive Care Med 32:660–667
  35. Martin J, Franck M, Fischer M, Spies C (2006) Sedation and analgesia in German intensive care units: how is it done in reality? Results of a patient-based survey of analgesia and sedation. Intensive Care Med 32:1137–1142
  36. Elliott R, McKinley S, Aitken LM, Hendrikz J (2006) The effect of an algorithm-based sedation guideline on the duration of mechanical ventilation in an Australian intensive care unit. Intensive Care Med 32:1506–1514
  37. Kompanje EJ, Bakker J, Slieker FJ, Ijzermans JN, Maas AI (2006) Reply to “Organ donation in pediatric traumatic brain injury” by Morris et al. Intensive Care Med 32:1448
  38. Sanner MA, Nydahl A, Desatnik P, Rizell M (2006) Obstacles to organ donation in Swedish intensive care units. Intensive Care Med 32:700–707
  39. Revelly JP, Imperatori L, Maravic P, Schaller MD, Chiolero R (2006) Are terminally ill patients dying in the ICU suitable for non-heart beating organ donation? Intensive Care Med 32:708–712
  40. Rundgren M, Rosen I, Friberg H (2006) Amplitude-integrated EEG (aEEG) predicts outcome after cardiac arrest and induced hypothermia. Intensive Care Med 32:836–842
  41. Sirgo G, Perez-Vela JL, Morales P, Del Rey M, Vendrell J, Gutierrez C, Rello J (2006) Association between 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene with stroke or encephalopathy after cardiac surgery. Intensive Care Med 32:668–675
  42. Chieregato A, Sabia G, Tanfani A, Compagnone C, Tagliaferri F, Targa L (2006) Xenon-CT and transcranial Doppler in poor-grade or complicated aneurysmatic subarachnoid hemorrhage patients undergoing aggressive management of intracranial hypertension. Intensive Care Med 32:1143–1150
  43. Grande PO (2006) The “Lund Concept” for the treatment of severe head trauma – physiological principles and clinical application. Intensive Care Med 32:1475–1484
  44. Andrews PJ, Citerio G (2006) Lund Therapy – pathophysiology-based therapy or contrived over-interpretation of limited data? Intensive Care Med 32:1461–1463
  45. Citerio G, Andrews PJ (2006) Refractory elevated intracranial pressure: intensivist's role in solving the dilemma of decompressive craniectomy. Intensive Care Med, DOI 10.1007/s00134-006-0381-5
  46. Leal-Noval SR, Rincon-Ferrari MD, Marin-Niebla A, Cayuela A, Arellano-Orden V, Marin-Caballos A, Amaya-Villar R, Ferrandiz-Millon C, Murillo-Cabeza F (2006) Transfusion of erythrocyte concentrates produces a variable increment on cerebral oxygenation in patients with severe traumatic brain injury: A preliminary study. Intensive Care Med 32:1733–1740
  47. Berg A, Bellander BM, Wanecek M, Gamrin L, Elving A, Rooyackers O, Ungerstedt U, Wernerman J (2006) Intravenous glutamine supplementation to head trauma patients leaves cerebral glutamate concentration unaffected. Intensive Care Med 32:1741–176
  48. Naredi S, Lambert G, Friberg P, Zall S, Eden E, Rydenhag B, Tylman M, Bengtsson A (2006) Sympathetic activation and inflammatory response in patients with subarachnoid haemorrhage. Intensive Care Med 32:1955–1961
  49. Inoue S, Kawaguchi M, Sasaoka N, Hirai K, Furuya H (2006) Effects of neuromuscular block on systemic and cerebral hemodynamics and bispectral index during moderate or deep sedation in critically ill patients. Intensive Care Med 32:391–397
  50. Koutsoukou A, Perraki H, Raftopoulou A, Koulouris N, Sotiropoulou C, Kotanidou A, Orfanos S, Roussos C (2006) Respiratory mechanics in brain-damaged patients. Intensive Care Med 32:1947–1954
  51. Mascia L (2006) Ventilatory setting in severe brain injured patients: does it really matter? Intensive Care Med 32:1925–1927
  52. Ronco C, Bellomo R, Homel P, Bendolan A, Dan M, Piccini P, La Greca G (2000) Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial.Lancet 356:26–30
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  53. Bouman C, Oudeman-Van Straaten H, Tijssen J, Zandstra D, Kesecioglu J (2002) Effects of high-volume continuous venovenous hemolfiltration on survival and recovery of renal function in intensive care patients with acute renal failure: a prospective, randomized trial. Crit Care Med 30:2205–2211
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  54. Ioannidis M (2006) Acute kidney injury in septic shock-do not under-treat. Intensive Care Med 32:18–20
  55. Piccinni P, Dan M, Barbacini S, Carraro R, Lieta E, Marafon S, Zamperetti N, Brendolan A, D'Intini V, Tetta C, Bellomo R, Ronco C (2006) Early isovolaemic haemofiltration in oliguric patients with septic shock. Intensive Care Med 32:80–86
  56. Cornejo R, Downey P, Castro R, Romero C, Regueira T, Vega J, Castillo L, Andresen M, Dougnac A, Bugedo G, Hernandez G (2006) High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock. Intensive Care Med 32:713–722
  57. Van Den Berghe G, Wilmer A, Hermans G, Meersseman W, Wouters P, Milants I, Van Wijngaerden E, Bobbaers H, Bouillon R (2006) Intensive insulin therapy in the medical ICU. N Engl J Med 354:449–461
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  58. Ligtenberg JJ, Meijering S, Stienstra Y, van der Horst IC, Vogelzang M, Nijsten MW, Tulleken JE, Zijlstra JG (2006) Mean glucose level is not an independent risk factor for mortality in mixed ICU patients. Intensive Care Med 32:435–438
  59. Mitchell I, Finfer S, Bellomo R, Higlett T (2006) Management of blood glucose in the critically ill in Australia and New Zealand: a practice survey and inception cohort study. Intensive Care Med 32:867–874
  60. Morel J, Venet C, Donati Y, Charier D, Liotier J, Frere-Meunier D, Guyomarc'h S, Diconne E, Bertrand JC, Souweine B, Papazian L, Zeni F (2006) Adrenal axis function does not appear to be associated with hemodynamic improvement in septic shock patients systematically receiving glucocorticoid therapy. Intensive Care Med 32:1184–1190
  61. Marik PE (2006) Adrenal-exhaustion syndrome in patients with liver disease. Intensive Care Med 32:275–280

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