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Volume 43, Number 11
November 2017

Impact factor


Seven-Day Profile Publication

Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trialOpen access

Melanie Meersch, Christoph Schmidt, Andreas Hoffmeier, Hugo Van Aken, Carola Wempe, Joachim Gerss, Alexander Zarbock
Pages 1551 - 1561

Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial

Martin B. Madsen, Peter B. Hjortrup, Marco B. Hansen, Theis Lange, Anna Norrby-Teglund, Ole Hyldegaard, Anders Perner
Pages 1585 - 1593

Early goal-directed nutrition versus standard of care in adult intensive care patients: the single-centre, randomised, outcome assessor-blinded EAT-ICU trial

Matilde Jo Allingstrup, Jens Kondrup, Jørgen Wiis, Casper Claudius, Ulf Gøttrup Pedersen, Rikke Hein-Rasmussen, Mads Rye Bjerregaard, Morten Steensen, Tom Hartvig Jensen, Theis Lange, Martin Bruun Madsen, Morten Hylander Møller, Anders Perner
Pages 1637 - 1647

Biomarker-based strategy for early discontinuation of empirical antifungal treatment in critically ill patients: a randomized controlled trial

Anahita Rouzé, Séverine Loridant, Julien Poissy, Benoit Dervaux, Boualem Sendid, Marjorie Cornu, Saad Nseir
Pages 1668 - 1677

Original Article

Impact of tapered-cuff tracheal tube on microaspiration of gastric contents in intubated critically ill patients: a multicenter cluster-randomized cross-over controlled trial

Emmanuelle Jaillette, Christophe Girault, Guillaume Brunin, Farid Zerimech, Hélène Behal, Arnaud Chiche, Céline Broucqsault-Dedrie, Cyril Fayolle, Franck Minacori, Isabelle Alves, Stéphanie Barrailler, Julien Labreuche, Laurent Robriquet, Fabienne Tamion, Emmanuel Delaporte, Damien Thellier, Claire Delcourte, Alain Duhamel, Saad Nseir
Pages 1562 - 1571

Randomized, multicenter trial of lateral Trendelenburg versus semirecumbent body position for the prevention of ventilator-associated pneumonia

Gianluigi Li Bassi, Mauro Panigada, Otavio T. Ranzani, Alberto Zanella, Lorenzo Berra, Massimo Cressoni, Vieri Parrini, Hassan Kandil, Giovanni Salati, Paola Selvaggi, Alessandro Amatu, Miquel Sanz-Moncosi, Emanuela Biagioni, Fernanda Tagliaferri, Mirella Furia, Giovanna Mercurio, Antonietta Costa, Tullio Manca, Simone Lindau, Jaksa Babel, Marco Cavana, Chiara Chiurazzi, Joan-Daniel Marti, Dario C
Pages 1572 - 1584

A randomized clinical trial of ultrasound-guided infra-clavicular cannulation of the subclavian vein in cardiac surgical patients: short-axis versus long-axis approach

Antonella Vezzani, Tullio Manca, Claudia Brusasco, Gregorio Santori, Luca Cantadori, Andrea Ramelli, Gianluca Gonzi, Francesco Nicolini, Tiziano Gherli, Francesco Corradi
Pages 1594 - 1601

Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial

Frank Bloos, Hendrik Rüddel, Daniel Thomas-Rüddel, Daniel Schwarzkopf, Christine Pausch, Stephan Harbarth, Torsten Schreiber, Matthias Gründling, John Marshall, Philipp Simon, Mitchell M. Levy, Manfred Weiss, Andreas Weyland, Herwig Gerlach, Tobias Schürholz, Christoph Engel, Claudia Matthäus-Krämer, Christian Scheer, Friedhelm Bach, Reimer Riessen, Bernhard Poidinger, Karin Dey, Norbert Weiler, A
Pages 1602 - 1612

Performance and economic evaluation of the molecular detection of pathogens for patients with severe infections: the EVAMICA open-label, cluster-randomised, interventional crossover trialOpen access

Emmanuelle Cambau, Isabelle Durand-Zaleski, Stéphane Bretagne, Christian Brun-Buisson, Catherine Cordonnier, Xavier Duval, Stéphanie Herwegh, Julien Pottecher, René Courcol, Sylvie Bastuji-Garin
Pages 1613 - 1625

Intermittent noninvasive ventilation after extubation in patients with chronic respiratory disorders: a multicenter randomized controlled trial (VHYPER)

Frédéric Vargas, Marc Clavel, Pascale Sanchez-Verlan, Sylvain Garnier, Alexandre Boyer, Hoang-Nam Bui, Benjamin Clouzeau, Charline Sazio, Aissa Kerchache, Olivier Guisset, Antoine Benard, Julien Asselineau, Bernard Gauche, Didier Gruson, Stein Silva, Philippe Vignon, Gilles Hilbert
Pages 1626 - 1636

Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndromeOpen access

Yongfang Zhou, Xiaodong Jin, Yinxia Lv, Peng Wang, Yunqing Yang, Guopeng Liang, Bo Wang, Yan Kang
Pages 1648 - 1659

Reconnection to mechanical ventilation for 1 h after a successful spontaneous breathing trial reduces reintubation in critically ill patients: a multicenter randomized controlled trial

M. Mar Fernandez, Alejandro González-Castro, Monica Magret, M. Teresa Bouza, Marcos Ibañez, Carolina García, Begoña Balerdi, Arantxa Mas, Vanesa Arauzo, José M. Añón, Francisco Ruiz, José Ferreres, Roser Tomás, Marta Alabert, Ana Isabel Tizón, Susana Altaba, Noemi Llamas, Rafael Fernandez
Pages 1660 - 1667

What's New in Intensive Care

Paediatric sepsis: old wine in new bottles?Open access

Luregn J. Schlapbach, Etienne Javouhey, Nicolaas J. G. Jansen
Pages 1686 - 1689

Recommendations for the management of severe malaria and severe dengue in resource-limited settingsOpen access

Arjen M. Dondorp, Mai Nguyen Thi Hoang, Mervyn Mer
Pages 1683 - 1685

Understanding the Disease

Understanding intensive care unit benchmarking

Jorge I. F. Salluh, Marcio Soares, Mark T. Keegan
Pages 1703 - 1707


Fixed minimum volume resuscitation: Pro

Flavia R. Machado, Mitchell M. Levy, Andrew Rhodes
Pages 1678 - 1680

Fixed minimum fluid volume for resuscitation: Con

Anders Perner, Mervyn Singer
Pages 1681 - 1682

Intensive Care Medicine in 2050: global perspectives

Yaseen M. Arabi, Marcus J. Schultz, Jorge I. F. Salluh
Pages 1695 - 1699

Beware the siren’s song of novel endotracheal tube designs

Michael Klompas, Lorenzo Berra, Richard Branson
Pages 1708 - 1711

Is it time to implement door-to-needle time for “infection attacks”?

Kevin B. Laupland, Ricard Ferrer
Pages 1712 - 1713

Real -time PCR for early microbiological diagnosis: is it time?

José-Artur Paiva, Kevin B. Laupland
Pages 1714 - 1716

Therapeutic targets in necrotizing soft tissue infections

Nicolas de Prost, Jeffrey Lipman, Olivier Mimoz
Pages 1717 - 1719

Optimal guidance for early nutrition therapy in critical illness?

Michael P. Casaer, Jean Reignier, Gordon Doig
Pages 1720 - 1722

Imaging in Intensive Care Medicine

Multistage ECMO cannulas: first holes get it all?

Philip Fortuna, Nuno Germano, Cristina José, Ana Martins
Pages 1725 - 1725

The dark side of the swan

Álvaro J. Roldán-Reina, Luis Martín-Villén, Yael Corcia-Palomo, Rafael Hinojosa-Pérez
Pages 1726 - 1727

Rare complication of femoral venous catheter malposition: abdominal compartment syndrome

Julianna Svantner, Philippe Eckert, Nawfel Ben-Hamouda
Pages 1728 - 1729

Clostridium perfringens related spleen gangrene

Guillaume Dumas, Jacques Tankovic, Naike Bigé, Eric Maury
Pages 1730 - 1731

From the Inside


The effect of high-dose cholecalciferol on bioavailable vitamin D levels in critically ill patients: a post hoc analysis of the VITdAL-ICU trial

Gennaro Martucci, Fabio Tuzzolino, Antonio Arcadipane, Thomas R. Pieber, Christian Schnedl, Tadeja Urbanic Purkart, Gerlies Treiber, Karin Amrein
Pages 1732 - 1734

High variability of treatments for paediatric status asthmaticus: a retrospective study in PICUs

Noëlle Lachaussée, François Angoulvant, Stéphane Dauger
Pages 1735 - 1737

Transthoracic echography assessment of the superior vena cava flow: a pilot study

Bertrand Dévigne, Guillaume Marcotte, Jullien Crozon-Clauzel, Benjamin Delwarde, Bernard Floccard, Serge Duperret, Thomas Rimmelé
Pages 1738 - 1739

The clinical picture of severe leptospirosis in critically ill patients

Khalid Abidi, T. Dendane, N. Madani, J. Belayachi, R. Abouqal, A. A. Zeggwagh
Pages 1740 - 1741

Risk factors of percutaneous cannulation failure by intensivists for veno-arterial extracorporeal life support for refractory cardiac arrest

V. Chhor, A. Follin, J. Joachim, B. Champigneulle, J. Chatelon, G. Favé, A. Neuschwander, J. Mantz, Romain Pirracchio
Pages 1742 - 1744

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