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Volume 42, Number 12
December 2016

Impact factor

10.125

Seven-Day Profile Publication

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

John G. Laffey, Giacomo Bellani, Tài Pham, Eddy Fan, Fabiana Madotto, Ednan K. Bajwa, Laurent Brochard, Kevin Clarkson, Andres Esteban, Luciano Gattinoni, Frank van Haren, Leo M. Heunks, Kiyoyasu Kurahashi, Jon Henrik Laake, Anders Larsson, Daniel F. McAuley, Lia McNamee, Nicolas Nin, Haibo Qiu, Marco Ranieri, Gordon D. Rubenfeld, B. Taylor Thompson, Hermann Wrigge, Arthur S. Slutsky, Antonio Pese
Pages 1865 - 1876

Apnoeic oxygenation via high-flow nasal cannula oxygen combined with non-invasive ventilation preoxygenation for intubation in hypoxaemic patients in the intensive care unit: the single-centre, blinded, randomised controlled OPTINIV trial

Samir Jaber, Marion Monnin, Mehdi Girard, Matthieu Conseil, Moussa Cisse, Julie Carr, Martin Mahul, Jean Marc Delay, Fouad Belafia, Gérald Chanques, Nicolas Molinari, Audrey De Jong
Pages 1877 - 1887

Original Article

Effect of early postextubation high-flow nasal cannula vs conventional oxygen therapy on hypoxaemia in patients after major abdominal surgery: a French multicentre randomised controlled trial (OPERA)

Emmanuel Futier, Catherine Paugam-Burtz, Thomas Godet, Linda Khoy-Ear, Sacha Rozencwajg, Jean-Marc Delay, Daniel Verzilli, Jeremie Dupuis, Gerald Chanques, Jean-Etienne Bazin, Jean-Michel Constantin, Bruno Pereira, Samir Jaber
Pages 1888 - 1898

Plasma cytokine levels predict response to corticosteroids in septic shock

Peter Bentzer, Chris Fjell, Keith R. Walley, John Boyd, James A. Russell
Pages 1970 - 1979

The effect of sepsis and its inflammatory response on mechanical clot characteristics: a prospective observational study

Gareth R. Davies, Suresh Pillai, Matthew Lawrence, Gavin M. Mills, Robert Aubrey, Lindsay D’Silva, Ceri Battle, Rhodri Williams, Rowan Brown, Dafydd Thomas, Keith Morris, Phillip Adrian Evans
Pages 1990 - 1998

Venoarterial extracorporeal membrane oxygenation for refractory cardiogenic shock post-cardiac arrest

Marc Pineton de Chambrun, Nicolas Bréchot, Guillaume Lebreton, Matthieu Schmidt, Guillaume Hekimian, Pierre Demondion, Jean-Louis Trouillet, Pascal Leprince, Jean Chastre, Alain Combes, Charles-Edouard Luyt
Pages 1999 - 2007

Review

Diagnosis and management of skin and soft tissue infections in the intensive care unit: a review

Jason P. Burnham, John P. Kirby, Marin H. Kollef
Pages 1899 - 1911

Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy

Anders Perner, Anthony C. Gordon, Daniel De Backer, George Dimopoulos, James A. Russell, Jeffrey Lipman, Jens-Ulrik Jensen, John Myburgh, Mervyn Singer, Rinaldo Bellomo, Timothy Walsh
Pages 1958 - 1969

Systematic Review

Control groups in recent septic shock trials: a systematic review

Ville Pettilä, Peter Buhl Hjortrup, Stephan M. Jakob, Erika Wilkman, Anders Perner, Jukka Takala
Pages 1912 - 1921

Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysisOpen access

Dagmar M. Ouweneel, Jasper V. Schotborgh, Jacqueline Limpens, Krischan D. Sjauw, A. E. Engström, Wim K. Lagrand, Thomas G. V. Cherpanath, Antoine H. G. Driessen, Bas A. J. M. de Mol, José P. S. Henriques
Pages 1922 - 1934

What's New in Intensive Care

What’s new in sepsis recognition in resource-limited settings?Open access

Arthur Kwizera, Emir Festic, Martin W. Dünser
Pages 2030 - 2033

Alternatives to antibiotics

Bruno François, Hasan S. Jafri, Marc Bonten
Pages 2034 - 2036

Pediatric sepsis and septic shock management in resource-limited settings

Ndidiamaka Musa, Srinivas Murthy, Niranjan Kissoon
Pages 2037 - 2039

What’s new on balanced crystalloid solutions?

Paul Young, Flavia R. Machado, Simon Finfer
Pages 2046 - 2048

Why biomarkers failed in sepsis

Jens-Ulrik Jensen, Lila Bouadma
Pages 2049 - 2051

What’s new in surgical treatment of infective endocarditis?

Thierry Carrel, Lars Englberger, Jukka Takala
Pages 2052 - 2054

Planet’s population on the move, infections on the rise

Garyphallia Poulakou, Diamantis Plachouras
Pages 2055 - 2058

Should we take into account ESBLs in empirical antibiotic treatment?

Bassetti Matteo, Jesús Rodríguez Baño
Pages 2059 - 2062

Understanding the Disease

Understanding antibiotic stewardship for the critically ill

J. J. De Waele, J. Schouten, G. Dimopoulos
Pages 2063 - 2065

Understanding why resistant bacteria are associated with higher mortality in ICU patients

François Barbier, Thiago Lisboa, Saad Nseir
Pages 2066 - 2069

Cardiac dysfunction in sepsis

Anders Aneman, Antoine Vieillard-Baron
Pages 2073 - 2076

Understanding circulatory failure in sepsis

Andreas Bloch, David Berger, Jukka Takala
Pages 2077 - 2079

Understanding resistance

François Barbier, Charles-Edouard Luyt
Pages 2080 - 2083

Understanding host–pathogen interaction

K. Asehnoune, J. Villadangos, R. S. Hotchkiss
Pages 2084 - 2086

Editorials

Sepsis: find me, manage me, and stop me!

Jean-Francois Timsit, Anders Perner
Pages 1851 - 1853

In sepsis, everything old is new again

Anthony Delaney, Flavia Machado
Pages 2008 - 2010

What patient data should be collected in this randomized controlled trial in sepsis?

Jean-Louis Vincent, Ignacio Martin-Loeches, Djillali Annane
Pages 2011 - 2013

In 2035, will all bacteria be multiresistant? Yes

George Dimopoulos, Marin H. Kollef, Jon Cohen
Pages 2014 - 2016

In 2035, will all bacteria be multidrug-resistant? No

François Barbier, Jeffrey Lipman, Marc J. M. Bonten
Pages 2017 - 2020

In 2035, will all bacteria be multidrug resistant? We are not sure

Kevin B. Laupland, Etienne Ruppé, Stephan Harbarth
Pages 2021 - 2023

The new sepsis consensus definitions: the good, the bad and the ugly

Charles L. Sprung, Roland M. H. Schein, Robert A. Balk
Pages 2024 - 2026

Imaging in Intensive Care Medicine

Common femoral artery pseudoaneurysm

Pablo Blanco, Carolina Godoy, Mariana Torre
Pages 2087 - 2088

Ultrasonographic diagnosis of tracheal compression

Oliviero Fochi, Moreno Favarato, Ezio Bonanomi
Pages 2089 - 2089

Kinking, thrombosis and need for re-operation in a patient with a left ventricular assist deviceOpen access

Rahat Muslem, Sakir Akin, Olivier Manintveld, Kadir Caliskan
Pages 2090 - 2091

Hypermucoviscous Klebsiella pneumoniae pneumonia: follow the string!

Manal Mazloum, Matthieu Le Meur, Guilene Barnaud, Jonathan Messika
Pages 2092 - 2093

An unusual, iatrogenic cause of massive airleak

Sofoklis Mitsos, Kelvin Lau
Pages 2094 - 2095

From the Inside

Transforming ICU death into life—radically more

Christos Lazaridis
Pages 2096 - 2097

Letter

De-escalation of pivotal beta-lactam in ventilator-associated pneumonia does not impact outcome and marginally affects MDR acquisition

E. Weiss, J. R. Zahar, M. Garrouste-Orgeas, S. Ruckly, W. Essaied, C. Schwebel, J. F. Timsit
Pages 2098 - 2100

Extremely high transpulmonary pressure in a spontaneously breathing patient with early severe ARDS on ECMO

Tommaso Mauri, Thomas Langer, Alberto Zanella, Giacomo Grasselli, Antonio Pesenti
Pages 2101 - 2103

Variability in frequency of consultation and needs assessed by palliative care services across multiple specialty ICUs

Benjamin Stix, Hannah Wunsch, Caitlin Clancy, Craig Blinderman, May Hua
Pages 2104 - 2105

CAST: a new score for early prediction of neurological outcomes after cardiac arrest before therapeutic hypothermia with high accuracyOpen access

Mitsuaki Nishikimi, Naoyuki Matsuda, Kota Matsui, Kunihiko Takahashi, Tadashi Ejima, Keibun Liu, Takayuki Ogura, Michiko Higashi, Hitoshi Umino, Go Makishi, Atsushi Numaguchi, Satoru Matsushima, Hideki Tokuyama, Mitsunobu Nakamura, Shigeyuki Matsui
Pages 2106 - 2107

Comparison of the qSOFA and CRB-65 for risk prediction in patients with community-acquired pneumonia

Martin Kolditz, André Scherag, Gernot Rohde, Santiago Ewig, Tobias Welte, Mathias Pletz
Pages 2108 - 2110

Focus Editorial

In Memoriam

ORIGINAL

Pediatric Original

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