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Changing use of noninvasive ventilation in critically ill patients: trends over 15 years in francophone countries

Alexandre Demoule| Sylvie Chevret| Annalisa Carlucci| Achille Kouatchet| Samir Jaber| Ferhat Meziani| Matthieu Schmidt| David Schnell| Céline Clergue| Jérôme Aboab| Antoine Rabbat| Béatrice Eon| Claude Guérin| Hugues Georges| Benjamin Zuber| Jean Dellamonica| Vincent Das| Joël Cousson| Didier Perez| Laurent Brochard| Elie Azoulay
Original
Volume 42, Issue 1 / January , 2016

Pages 82 - 92

Abstract

Purpose

Over the last two decades, noninvasive ventilation (NIV) has been proposed in various causes of acute respiratory failure (ARF) but some indications are debated. Current trends in NIV use are unknown.

Methods

Comparison of three multicenter prospective audits including all patients receiving mechanical ventilation and conducted in 1997, 2002, and 2011 in francophone countries.

Results

Among the 4132 patients enrolled, 2094 (51 %) required ventilatory support for ARF and 2038 (49 %) for non-respiratory conditions. Overall NIV use was markedly increased in 2010/11 compared to 1997 and 2002 (37 % of mechanically ventilated patients vs. 16 % and 28 %, P < 0.05). In 2010/11, the use of first-line NIV for ARF had reached a plateau (24 % vs. 16 % and 23 %, P < 0.05) whereas pre-ICU and post-extubation NIV had substantially increased (11 % vs. 4 % and 11 % vs. 7 %, respectively, P < 0.05). First-line NIV remained stable in acute-on-chronic RF, continued to increase in cardiogenic pulmonary edema, but decreased in de novo ARF (16 % in 2010/11 vs. 23 % in 2002, P < 0.05). The NIV success rate increased from 56 % in 2002 to 70 % in 2010/11 and remained the lowest in de novo ARF. NIV failure in de novo ARF was associated with increased mortality in 2002 but not in 2010/11. Mortality decreased over time, and overall, NIV use was associated with a lower mortality.

Conclusion

Increases in NIV use and success rate, an overall decrease in mortality, and a decrease of the adverse impact NIV failure has in de novo ARF suggest better patient selection and greater proficiency of staff in administering NIV.

Trial registration

Clinicaltrials.gov Identifier NCT01449331.

Keywords

References

  1. Brochard L, Mancebo J, Wysocki M, Lofaso F, Conti G, Rauss A, Simonneau G, Benito S, Gasparetto A, Lemaire F (1995) Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 333:817–822
    • View reference on publisher's website
    • View reference on PubMed
  2. Keenan SP, Sinuff T, Cook DJ, Hill NS (2003) Which patients with acute exacerbation of chronic obstructive pulmonary disease benefit from noninvasive positive-pressure ventilation? A systematic review of the literature. Ann Intern Med 138:861–870
    • View reference on publisher's website
    • View reference on PubMed
  3. Masip J, Roque M, Sanchez B, Fernandez R, Subirana M, Exposito JA (2005) Noninvasive ventilation in acute cardiogenic pulmonary edema: systematic review and meta-analysis. JAMA 294:3124–3130
    • View reference on publisher's website
    • View reference on PubMed
  4. Hilbert G, Gruson D, Vargas F, Valentino R, Gbikpi-Benissan G, Dupon M, Reiffers J, Cardinaud JP (2001) Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure. N Engl J Med 344:481–487
    • View reference on publisher's website
    • View reference on PubMed
  5. Antonelli M, Conti G, Bufi M, Costa MG, Lappa A, Rocco M, Gasparetto A, Meduri GU (2000) Noninvasive ventilation for treatment of acute respiratory failure in patients undergoing solid organ transplantation: a randomized trial. JAMA 283:235–241
    • View reference on publisher's website
    • View reference on PubMed
  6. Carlucci A, Richard JC, Wysocki M, Lepage E, Brochard L (2001) Noninvasive versus conventional mechanical ventilation. An epidemiologic survey. Am J Respir Crit Care Med 163:874–880
    • View reference on publisher's website
    • View reference on PubMed
  7. Demoule A, Girou E, Richard JC, Taille S, Brochard L (2006) Increased use of noninvasive ventilation in French intensive care units. Intensive Care Med 32:1747–1755
  8. Park M, Sangean MC, Volpe Mde S, Feltrim MI, Nozawa E, Leite PF, Passos Amato MB, Lorenzi-Filho G (2004) Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema. Crit Care Med 32:2407–2415
    • View reference on publisher's website
    • View reference on PubMed
  9. Giacomini M, Iapichino G, Cigada M, Minuto A, Facchini R, Noto A, Assi E (2003) Short-term noninvasive pressure support ventilation prevents ICU admittance in patients with acute cardiogenic pulmonary edema. Chest 123:2057–2061
    • View reference on publisher's website
    • View reference on PubMed
  10. Ferrer M, Sellares J, Valencia M, Carrillo A, Gonzalez G, Badia JR, Nicolas JM, Torres A (2009) Non-invasive ventilation after extubation in hypercapnic patients with chronic respiratory disorders: randomised controlled trial. Lancet 374:1082–1088
    • View reference on publisher's website
    • View reference on PubMed
  11. Chiumello D, Chevallard G, Gregoretti C (2011) Non-invasive ventilation in postoperative patients: a systematic review. Intensive Care Med 37:918–929
  12. Chiumello D, Coppola S, Froio S, Gregoretti C, Consonni D (2013) Noninvasive ventilation in chest trauma: systematic review and meta-analysis. Intensive Care Med 39:1171–1180
  13. Conférence de consensus commune (SRLF-SPLF-SFAR) (2006) Ventilation non invasive dans l’insuffisnce respiratoire aiguë. Réanimation 6
  14. Esteban A, Ferguson ND, Meade MO, Frutos-Vivar F, Apezteguia C, Brochard L, Raymondos K, Nin N, Hurtado J, Tomicic V, Gonzalez M, Elizalde J, Nightingale P, Abroug F, Pelosi P, Arabi Y, Moreno R, Jibaja M, D’Empaire G, Sandi F, Matamis D, Montanez AM, Anzueto A (2008) Evolution of mechanical ventilation in response to clinical research. Am J Respir Crit Care Med 177:170–177
    • View reference on publisher's website
    • View reference on PubMed
  15. Esteban A, Frutos-Vivar F, Muriel A, Ferguson ND, Penuelas O, Abraira V, Raymondos K, Rios F, Nin N, Apezteguia C, Violi DA, Thille AW, Brochard L, Gonzalez M, Villagomez AJ, Hurtado J, Davies AR, Du B, Maggiore SM, Pelosi P, Soto L, Tomicic V, D’Empaire G, Matamis D, Abroug F, Moreno RP, Soares MA, Arabi Y, Sandi F, Jibaja M, Amin P, Koh Y, Kuiper MA, Bulow HH, Zeggwagh AA, Anzueto A (2013) Evolution of mortality over time in patients receiving mechanical ventilation. Am J Respir Crit Care Med 188:220–230
    • View reference on publisher's website
    • View reference on PubMed
  16. Demoule A, Chevret S, Kouatchet A, Jaber S, Meziani F, Schmidt M, Schnell D, Clergue C, Aboab J, Rabbat A, Lambert D, Guerin C, Georges H, Zuber B, Dellamonica J, Das V, Cousson J, Drault J, Kalfon P, Perez D, Forceville X, Depuyt P, Jacobs F, Legrand M, Lambert J, Castanier M, Brochard L, Azoulay E (2013) Understanding noninvasive mechanical ventilation success in French and Belgian ICUs. Am J Respir Crit Care Med 187:A5724
  17. Azoulay E, Kouatchet A, Jaber S, Lambert J, Meziani F, Schmidt M, Schnell D, Mortaza S, Conseil M, Tchenio X, Herbecq P, Andrivet P, Guerot E, Lafabrie A, Perbet S, Camous L, Janssen-Langenstein R, Collet F, Messika J, Legriel S, Fabre X, Guisset O, Touati S, Kilani S, Alves M, Mercat A, Similowski T, Papazian L, Meert AP, Chevret S, Schlemmer B, Brochard L, Demoule A (2013) Noninvasive mechanical ventilation in patients having declined tracheal intubation. Intensive Care Med 39:292–301
  18. Schnell D, Timsit JF, Darmon M, Vesin A, Goldgran-Toledano D, Dumenil AS, Garrouste-Orgeas M, Adrie C, Bouadma L, Planquette B, Cohen Y, Schwebel C, Soufir L, Jamali S, Souweine B, Azoulay E (2014) Noninvasive mechanical ventilation in acute respiratory failure: trends in use and outcomes. Intensive Care Med 40:582–591
  19. Le Gall JR, Lemeshow S, Saulnier F (1993) A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 270:2957–2963
    • View reference on publisher's website
    • View reference on PubMed
  20. Curtis JR, Cook DJ, Sinuff T, White DB, Hill N, Keenan SP, Benditt JO, Kacmarek R, Kirchhoff KT, Levy MM (2007) Noninvasive positive pressure ventilation in critical and palliative care settings: understanding the goals of therapy. Crit Care Med 35:932–939
    • View reference on publisher's website
    • View reference on PubMed
  21. Azoulay E, Kouatchet A, Jaber S, Meziani F, Papazian L, Brochard L, Demoule A (2013) Non-invasive ventilation for end-of-life oncology patients. Lancet Oncol 14:e200–e201
    • View reference on publisher's website
    • View reference on PubMed
  22. Esteban A, Anzueto A, Alia I, Gordo F, Apezteguia C, Palizas F, Cide D, Goldwaser R, Soto L, Bugedo G, Rodrigo C, Pimentel J, Raimondi G, Tobin MJ (2000) How is mechanical ventilation employed in the intensive care unit? An international utilization review. Am J Respir Crit Care Med 161:1450–1458
    • View reference on publisher's website
    • View reference on PubMed
  23. Esteban A, Frutos-Vivar F, Ferguson ND, Meade MO, Anzueto A, Brochard L, Alia I, Nightingale P, Pelosi P, D’Empaire G, Arabi Y, Abroug F, Apezteguia C, Tomicic V, Nin N, Tejerina E, Turan G, Gonzalez M, Hurtado J, Raymondos K, David CM (2006) Evaluation in the use of non-invasive ventilation in the ICU. Proc Am Thorac Soc 3:A472
    • View reference on publisher's website
  24. Thys F, Roeseler J, Reynaert M, Liistro G, Rodenstein DO (2002) Noninvasive ventilation for acute respiratory failure: a prospective randomised placebo-controlled trial. Eur Respir J 20:545–555
    • View reference on publisher's website
    • View reference on PubMed
  25. Wood KA, Lewis L, Von Harz B, Kollef MH (1998) The use of noninvasive positive pressure ventilation in the emergency department: results of a randomized clinical trial. Chest 113:1339–1346
    • View reference on publisher's website
    • View reference on PubMed
  26. L’Her E, Duquesne F, Girou E, de Rosiere XD, Le Conte P, Renault S, Allamy JP, Boles JM (2004) Noninvasive continuous positive airway pressure in elderly cardiogenic pulmonary edema patients. Intensive Care Med 30:882–888
  27. Vaschetto R, Turucz E, Dellapiazza F, Guido S, Colombo D, Cammarota G, Della Corte F, Antonelli M, Navalesi P (2012) Noninvasive ventilation after early extubation in patients recovering from hypoxemic acute respiratory failure: a single-centre feasibility study. Intensive Care Med 38:1599–1606
  28. Demoule A, Girou E, Richard JC, Taille S, Brochard L (2006) Benefits and risks of success or failure of noninvasive ventilation. Intensive Care Med 32:1756–1765
  29. Evans TW (2001) International Consensus Conferences in Intensive Care Medicine: non-invasive positive pressure ventilation in acute respiratory failure. Intensive Care Med 27:166–178
  30. Funk GC, Bauer P, Burghuber OC, Fazekas A, Hartl S, Hochrieser H, Schmutz R, Metnitz P (2013) Prevalence and prognosis of COPD in critically ill patients between 1998 and 2008. Eur Respir J 41:792–799
    • View reference on publisher's website
    • View reference on PubMed
  31. Ozyilmaz E, Ugurlu AO, Nava S (2014) Timing of noninvasive ventilation failure: causes, risk factors, and potential remedies. BMC Pulm Med 14:19
    • View reference on publisher's website
    • View reference on PubMed
  32. Carteaux G, Lyazidi A, Cordoba-Izquierdo A, Vignaux L, Jolliet P, Thille AW, Richard JC, Brochard L (2012) Patient-ventilator asynchrony during noninvasive ventilation: a bench and clinical study. Chest 142:367–376
    • View reference on publisher's website
    • View reference on PubMed
  33. Vignaux L, Tassaux D, Jolliet P (2007) Performance of noninvasive ventilation modes on ICU ventilators during pressure support: a bench model study. Intensive Care Med 33:1444–1451
  34. Olivieri C, Costa R, Spinazzola G, Ferrone G, Longhini F, Cammarota G, Conti G, Navalesi P (2013) Bench comparative evaluation of a new generation and standard helmet for delivering non-invasive ventilation. Intensive Care Med 39:734–738
  35. Chandra D, Stamm JA, Taylor B, Ramos RM, Satterwhite L, Krishnan JA, Mannino D, Sciurba FC, Holguin F (2012) Outcomes of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease in the United States, 1998–2008. Am J Respir Crit Care Med 185:152–159
    • View reference on publisher's website
    • View reference on PubMed
  36. Dres M, Tran TC, Aegerter P, Rabbat A, Guidet B, Huchon G, Roche N (2013) Influence of ICU case-volume on the management and hospital outcomes of acute exacerbations of chronic obstructive pulmonary disease. Crit Care Med 41:1884–1892
    • View reference on publisher's website
    • View reference on PubMed
  37. Esteban A, Anzueto A, Frutos F, Alia I, Brochard L, Stewart TE, Benito S, Epstein SK, Apezteguia C, Nightingale P, Arroliga AC, Tobin MJ (2002) Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. JAMA 287:345–355
    • View reference on publisher's website
    • View reference on PubMed
  38. Conti G, Antonelli M, Navalesi P, Rocco M, Bufi M, Spadetta G, Meduri GU (2002) Noninvasive vs. conventional mechanical ventilation in patients with chronic obstructive pulmonary disease after failure of medical treatment in the ward: a randomized trial. Intensive Care Med 28:1701–1707
  39. Diaz GG, Alcaraz AC, Talavera JC, Perez PJ, Rodriguez AE, Cordoba FG, Hill NS (2005) Noninvasive positive-pressure ventilation to treat hypercapnic coma secondary to respiratory failure. Chest 127:952–960
    • View reference on publisher's website
    • View reference on PubMed
  40. Antonelli M, Conti G, Bello G (2013) New niches for NIV: ahead with caution! Intensive Care Med 39:1325–1327
  41. Azoulay E, Lemiale V, Mokart D, Pene F, Kouatchet A, Perez P, Vincent F, Mayaux J, Benoit D, Bruneel F, Meert AP, Nyunga M, Rabbat A, Darmon M (2014) Acute respiratory distress syndrome in patients with malignancies. Intensive Care Med 40:1106–1114
  42. Auriant I, Jallot A, Herve P, Cerrina J, Le Roy Ladurie F, Fournier JL, Lescot B, Parquin F (2001) Noninvasive ventilation reduces mortality in acute respiratory failure following lung resection. Am J Respir Crit Care Med 164:1231–1235
    • View reference on publisher's website
    • View reference on PubMed
  43. Lorut C, Lefebvre A, Planquette B, Quinquis L, Clavier H, Santelmo N, Abou Hanna H, Bellenot F, Regnard JF, Riquet M, Magdeleinat P, Meyer G, Roche N, Huchon G, Coste J, Rabbat A (2014) Early postoperative prophylactic noninvasive ventilation after major lung resection in COPD patients: a randomized controlled trial. Intensive Care Med 40:220–227
  44. Ferrer M, Esquinas A, Leon M, Gonzalez G, Alarcon A, Torres A (2003) Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial. Am J Respir Crit Care Med 168:1438–1444
    • View reference on publisher's website
    • View reference on PubMed

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