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Outcome measures report different aspects of patient function three months following critical care

Linda Denehy| Amy Nordon-Craft| Lara Edbrooke| Daniel Malone| Sue Berney| Margaret Schenkman| Marc Moss
Original
Volume 40, Issue 12 / December , 2014

Pages 1862 - 1869

Abstract

Background

Previous investigation of the relationship between physical performance and patient self-report physical function (PF) measures in intensive care unit (ICU) survivors have not been performed.

Objectives

To (1) analyze the extent to which other activity-based measures of physical performance may serve as proxies for the 6-min walk test (6MWT); (2) determine the extent to which the Short Form (SF) 36 domain of PF and physical component summary (PCS) score, reflect components of physical performance and (3) examine the relationship between demographic and ICU variables and the 6MWT.

Design

Cross-sectional data from two clinical trials.

Setting

Two acute care hospitals (Melbourne, Australia and Denver, USA).

Patients

A total of 177 survivors of ICU.

Measurements

Were evaluated at 3 months. Performance-based measures were: 6MWT, timed up and go test (TUG), the five times sit to stand test (5×STS), the Berg balance scale (BBS) and two self-report measures: the SF-36 PF domain and the PCS score.

Main results

6MWT showed excellent correlation with the TUG (rho = −0.79) and BBS (rho = 0.80); and good correlation with 5×STS (rho = −0.69) and SF-36 PF scores (rho = 0.69). 6MWT explained 54 and 33 % of variance in SF-36 PF and PCS scores respectively. No variables were clinically important in predicting 6MWT.

Conclusions

The 6MWT and TUG may both be acceptable measures of PF performance 3 months after ICU. Performance-based tests measure different constructs than self-report measures and choice of outcome variables should be aligned with study aims to ensure the most appropriate measure is used.

Keywords

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