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De-escalation in severe sepsis: still an important part of our armamentarium against antimicrobial resistance, of course!

Marc Leone| Carole Bechis| Karine Baumstarck
Correspondence
Volume 40, Issue 10 / October , 2014

Page 1619

No abstract available.

References

  1. Kapoor G, Saigal S (2014) De-escalation in severe sepsis: still an important part of our armamentarium against antimicrobial resistance. Intensive Care Med. doi:10.1007/s00134-014-3476-4
  2. Leone M, Bechis C, Baumstarck K, Lefrant JY, Albanèse J, Jaber S, Lepape A, Constantin JM, Papazian L, Bruder N, Allaouchiche B, Bézulier K, Antonini F, Textoris J, Martin C, for the AZUREA Network Investigators (2014) De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial. Intensive Care Med. doi:10.1007/s00134-014-3411-8
  3. Leone M, Bourgoin A, Cambon S, Dubuc M, Albanèse J, Martin C (2003) Empirical antimicrobial therapy of septic shock patients: adequacy and impact on the outcome. Crit Care Med 31:462–467
    • View reference on PubMed
    • View reference on publisher's website
  4. Mokart D, Slehofer G, Lambert J, Sannini A, Chow-Chine L, Brun JP, Berger P, Duran S, Faucher M, Blache JL, Saillard C, Vey N, Leone M (2014) De-escalation of antimicrobial treatment in neutropenic patients with severe sepsis: results from an observational study. Intensive Care Med 40:41–49
  5. Garnacho-Montero J, Gutiérrez-Pizarraya A, Escoresca-Ortega A, Corcia-Palomo Y, Fernández-Delgado E, Herrera-Melero I, Ortiz-Leyba C, Márquez-Vácaro JA (2014) De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock. Intensive Care Med 40:32–40

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