Log in | Register

Candida colonization of respiratory tract: to treat or not to treat, will we ever get an answer?

Gennaro De Pascale| Massimo Antonelli
Editorial
Volume 40, Issue 9 / September , 2014

Pages 1381 - 1384

No abstract available.

References

  1. Bassetti M, Righi E, Ansaldi F, Merelli M, Cecilia T, De Pascale G, Diaz-Martin A, Luzzati R, Rosin C, Lagunes L, Trecarichi EM, Sanguinetti M, Posteraro B, Garnacho-Montero J, Sartor A, Rello J, Rocca GD, Antonelli M, Tumbarello M (2014) A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality. Intensive Care Med 40:839–845
  2. Meersseman W, Lagrou K, Spriet I, Maertens J, Verbeken E, Peetermans WE, Van Wijngaerden E (2009) Significance of the isolation of Candida species from airway samples in critically ill patients: a prospective, autopsy study. Intensive Care Med 35:1526–1531
  3. Roux D, Gaudry S, Dreyfuss D, El-Benna J, de Prost N, Denamur E, Saumon G, Ricard JD (2009) Candida albicans impairs macrophage function and facilitates Pseudomonas aeruginosa pneumonia in rat. Crit Care Med 37:1062–1067
    • View reference on PubMed
    • View reference on publisher's website
  4. Ader F, Jawhara S, Nseir S, Kipnis E, Faure K, Vuotto F, Chemani C, Sendid B, Poulain D, Guery B (2011) Short term Candida albicans colonization reduces Pseudomonas aeruginosa-related lung injury and bacterial burden in a murine model. Crit Care 15:R150
    • View reference on PubMed
    • View reference on publisher's website
  5. Roux D, Gaudry S, Khoy-Ear L, Aloulou M, Phillips-Houlbracq M, Bex J, Skurnik D, Denamur E, Monteiro RC, Dreyfuss D, Ricard JD (2013) Airway fungal colonization compromises the immune system allowing bacterial pneumonia to prevail. Crit Care Med 41:e191–e199
    • View reference on PubMed
    • View reference on publisher's website
  6. Azoulay E, Timsit JF, Tafflet M, de Lassence A, Darmon M, Zahar JR, Adrie C, Garrouste-Orgeas M, Cohen Y, Mourvillier B, Schlemmer B, Outcomerea Study Group (2006) Candida colonization of the respiratory tract and subsequent pseudomonas ventilator-associated pneumonia. Chest 129:110–117
    • View reference on PubMed
    • View reference on publisher's website
  7. Nseir S, Jozefowicz E, Cavestri B, Sendid B, Di Pompeo C, Dewavrin F, Favory R, Roussel-Delvallez M, Durocher A (2007) Impact of antifungal treatment on Candida–Pseudomonas interaction: a preliminary retrospective case-control study. Intensive Care Med 33:137–142
  8. Delisle MS, Williamson DR, Perreault MM, Albert M, Jiang X, Heyland DK (2008) The clinical significance of Candida colonization of respiratory tract secretions in critically ill patients. J Crit Care 23:11–17
    • View reference on PubMed
    • View reference on publisher's website
  9. Williamson DR, Albert M, Perreault MM, Delisle MS, Muscedere J, Rotstein C, Jiang X, Heyland DK (2011) The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia. Can J Anaesth 58:275–284
    • View reference on PubMed
    • View reference on publisher's website
  10. Heyland D, Jiang X, Day AG, Laverdiere M (2011) Serum β-d-glucan of critically ill patients with suspected ventilator-associated pneumonia: preliminary observations. J Crit Care 26:536.e1–9
  11. Delisle MS, Williamson DR, Albert M, Perreault MM, Jiang X, Day AG, Heyland DK (2011) Impact of Candida species on clinical outcomes in patients with suspected ventilator-associated pneumonia. Can Respir J 8:131–136
  12. Hamet M, Pavon A, Dalle F, Pechinot A, Prin S, Quenot JP, Charles PE (2012) Candida spp. airway colonization could promote antibiotic-resistant bacteria selection in patients with suspected ventilator-associated pneumonia. Intensive Care Med 38:1272–1279
  13. Ong DS, Mc Klein Klouwenberg P, Spitoni C, Bonten MJ, Cremer OL (2013) Nebulised amphotericin B to eradicate Candida colonisation from the respiratory tract in critically ill patients receiving selective digestive decontamination: a cohort study. Crit Care 17:R233
    • View reference on PubMed
    • View reference on publisher's website
  14. Morales DK, Hogan DA (2010) Candida albicans interactions with bacteria in the context of human health and disease. PLoS Pathog 6:e1000886
    • View reference on PubMed
    • View reference on publisher's website
  15. Albert M, Williamson D, Muscedere J, Lauzier F, Roystein C, Kanji S, Jang X, Hall M, Heyland D (2014) Candida in the respiratory tract secretions of critically ill patients and the impact of antifungal treatment: a randomised placebo-controlled pilot trial (CANTREAT study). Intensive Care Med. doi:10.1007/s00134-014-3352-2
    • View reference on PubMed
  16. Mietto C, Pinciroli R, Patel N, Berra L (2013) Ventilator associated pneumonia: evolving definitions and preventive strategies. Respir Care 58:990–1007
    • View reference on PubMed
    • View reference on publisher's website
  17. Prigitano A, Dho G, Lazzarini C, Ossi C, Cavanna C, Tortorano AM, ECMM-FIMUA study group (2012) Biofilm production by Candida isolates from a survey of invasive fungal infections in Italian intensive care units. J Chemother 24:61–63
    • View reference on PubMed
    • View reference on publisher's website
  18. Posteraro B, De Pascale G, Tumbarello M, Torelli R, Pennisi MA, Bello G, Maviglia R, Fadda G, Sanguinetti M, Antonelli M (2011) Early diagnosis of candidemia in intensive care unit patients with sepsis: a prospective comparison of (1 → 3)-β-D-glucan assay, Candida score, and colonization index. Crit Care 15:R249
    • View reference on PubMed
    • View reference on publisher's website

Sign In

Connect with ICM

Top 5 Articles Editors Picks Supplement