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What’s new in organ donation: better care of the dead for the living

Ali Al-Khafaji| Raghavan Murugan| John A. Kellum
What's New in Intensive Care
Volume 39, Issue 11 / November , 2013

Pages 2031 - 2033

No abstract available.

References

  1. Israni AK, Zaun DA, Rosendale JD, Snyder JJ, Kasiske BL (2013) OPTN/SRTR 2011 annual data report: deceased organ donation. Am J Transplant 13(Suppl 1):179–198
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  2. McKeown DW, Bonser RS, Kellum JA (2012) Management of the heartbeating brain-dead organ donor. Br J Anaesth 108(Suppl 1):i96–i107
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  3. Murugan R, Venkataraman R, Wahed AS, Elder M, Hergenroeder G, Carter M, Madden NJ, Powner D, Kellum JA (2008) Increased plasma interleukin-6 in donors is associated with lower recipient hospital-free survival after cadaveric organ transplantation. Crit Care Med 36:1810–1816
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  4. Murugan R, Venkataraman R, Wahed AS, Elder M, Carter M, Madden NJ, Kellum JA (2009) Preload responsiveness is associated with increased interleukin-6 and lower organ yield from brain-dead donors. Crit Care Med 37:2387–2393
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  5. Perez-Blanco A, Caturla-Such J, Canovas-Robles J, Sanchez-Paya J (2005) Efficiency of triiodothyronine treatment on organ donor hemodynamic management and adenine nucleotide concentration. Intensive Care Med 31:943–948
  6. Venkateswaran RV, Patchell VB, Wilson IC, Mascaro JG, Thompson RD, Quinn DW, Stockley RA, Coote JH, Bonser RS (2008) Early donor management increases the retrieval rate of lungs for transplantation. Ann Thorac Surg 85(1):278–286 (discussion 286)
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  7. Pennefather SH, Bullock RE, Dark JH (1993) The effect of fluid therapy on alveolar arterial oxygen gradient in brain-dead organ donors. Transplantation 56:1418–1422
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  8. Gattas DJ, Dan A, Myburgh J, Billot L, Lo S, Finfer S (2013) Fluid resuscitation with 6% hydroxyethyl starch (130/0.4 and 130/0.42) in acutely ill patients: systematic review of effects on mortality and treatment with renal replacement therapy. Intensive Care Med 39:558–568
  9. Mascia L, Pasero D, Slutsky AS, Arguis MJ, Berardino M, Grasso S, Munari M, Boifava S, Cornara G, Della Corte F, Vivaldi N, Malacarne P, Del Gaudio P, Livigni S, Zavala E, Filippini C, Martin EL, Donadio PP, Mastromauro I, Ranieri VM (2010) Effect of a lung protective strategy for organ donors on eligibility and availability of lungs for transplantation: a randomized controlled trial. JAMA 304:2620–2627
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  10. Al-Khafaji A, Murugan R, Wahed A, Lebovitz DJ, Souter MJ, Kellum JA (2013) Monitoring Organ Donors to Improve Transplantation Results (MOnIToR) trial methodology. Crit Care Resusc (in press)
  11. Kellum JA, Venkataraman R, Powner D, Elder M, Hergenroeder G, Carter M (2008) Feasibility study of cytokine removal by hemoadsorption in brain-dead humans. Crit Care Med 36:268–272
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  12. Mikhova KM, Don CW, Laflamme M, Kellum JA, Mulligan, Verrier ED, Rabkin DG (2013) Effect of cytokine hemoadsorption on brain death-induced ventricular dysfunction in a porcine model. J Thorac Cardiovasc Surg 145:215–223 discussion 223-214
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  13. Antonelli M, Bonten M, Chastre J, Citerio G, Conti G, Curtis JR, De Backer D, Hedenstierna G, Joannidis M, Macrae D, Mancebo J, Maggiore SM, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H (2012) Year in review in Intensive Care Medicine 2011: I. Nephrology, epidemiology, nutrition and therapeutics, neurology, ethical and legal issues, experimentals. Intensive Care Med 38:192–209
  14. de Groot YJ, Wijdicks EF, van der Jagt M, Bakker J, Lingsma HF, Ijzermans JN, Kompanje EJ (2011) Donor conversion rates depend on the assessment tools used in the evaluation of potential organ donors. Intensive Care Med 37:665–670
  15. Kutsogiannis DJ, Asthana S, Townsend, Singh G, Karvellas CJ (2013) The incidence of potential missed organ donors in intensive care units and emergency rooms: a retrospective cohort. Intensive Care Med 39:1452–1459

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