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Year in review in Intensive Care Medicine 2011: III. ARDS and ECMO, weaning, mechanical ventilation, noninvasive ventilation, pediatrics and miscellaneaOpen access

Massimo Antonelli| Marc Bonten| Jean Chastre| Giuseppe Citerio| Giorgio Conti| J. Randall Curtis| Daniel De Backer| Goran Hedenstierna| Michael Joannidis| Duncan Macrae| Jordi Mancebo| Salvatore M. Maggiore| Alexandre Mebazaa| Jean-Charles Preiser| Patricia Rocco| Jean-François Timsit| Jan Wernerman| Haibo Zhang
Year in Review 2011
Volume 38, Issue 4 / April , 2012

Pages 542 - 556

No abstract available.


  1. Villar J, Blanco J, Anon JM, Santos-Bouza A, Blanch L, Ambros A, Gandia F, Carriedo D, Mosteiro F, Basaldua S, Fernandez RL, Kacmarek RM (2011) The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation. Intensive Care Med 37:1932–1941
  2. Dellamonica J, Lerolle N, Sargentini C, Beduneau G, Di Marco F, Mercat A, Richard JC, Diehl JL, Mancebo J, Rouby JJ, Lu Q, Bernardin G, Brochard L (2011) PEEP-induced changes in lung volume in acute respiratory distress syndrome. Two methods to estimate alveolar recruitment. Intensive Care Med 37:1595–1604
  3. Arnal JM, Paquet J, Wysocki M, Demory D, Donati S, Granier I, Corno G, Durand-Gasselin J (2011) Optimal duration of a sustained inflation recruitment maneuver in ARDS patients. Intensive Care Med 37:1588–1594
  4. Marini JJ (2011) Recruitment by sustained inflation: time for a change. Intensive Care Med 37:1572–1574
  5. Charron C, Bouferrache K, Caille V, Castro S, Aegerter P, Page B, Jardin F, Vieillard-Baron A (2011) Routine prone positioning in patients with severe ARDS: feasibility and impact on prognosis. Intensive Care Med 37:785–790
  6. Mentzelopoulos SD, Theodoridou M, Malachias S, Sourlas S, Exarchos DN, Chondros D, Roussos C, Zakynthinos SG (2011) Scanographic comparison of high frequency oscillation with versus without tracheal gas insufflation in acute respiratory distress syndrome. Intensive Care Med 37:990–999
  7. Nair P, Davies AR, Beca J, Bellomo R, Ellwood D, Forrest P, Jackson A, Pye R, Seppelt I, Sullivan E, Webb S (2011) Extracorporeal membrane oxygenation for severe ARDS in pregnant and postpartum women during the 2009 H1N1 pandemic. Intensive Care Med 37:648–654
  8. Forrest P, Ratchford J, Burns B, Herkes R, Jackson A, Plunkett B, Torzillo P, Nair P, Granger E, Wilson M, Pye R (2011) Retrieval of critically ill adults using extracorporeal membrane oxygenation: an Australian experience. Intensive Care Med 37:824–830
  9. Patroniti N, Zangrillo A, Pappalardo F, Peris A, Cianchi G, Braschi A, Iotti GA, Arcadipane A, Panarello G, Ranieri VM, Terragni P, Antonelli M, Gattinoni L, Oleari F, Pesenti A (2011) The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks. Intensive Care Med 37:1447–1457
  10. Costa R, Spinazzola G, Cipriani F, Ferrone G, Festa O, Arcangeli A, Antonelli M, Proietti R, Conti G (2011) A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV). Intensive Care Med 37:1494–1500
  11. Roze H, Lafrikh A, Perrier V, Germain A, Dewitte A, Gomez F, Janvier G, Ouattara A (2011) Daily titration of neurally adjusted ventilatory assist using the diaphragm electrical activity. Intensive Care Med 37:1087–1094
  12. Piquilloud L, Vignaux L, Bialais E, Roeseler J, Sottiaux T, Laterre PF, Jolliet P, Tassaux D (2011) Neurally adjusted ventilatory assist improves patient–ventilator interaction. Intensive Care Med 37:263–271
  13. Tuchscherer D, Z’Graggen WJ, Passath C, Takala J, Sinderby C, Brander L (2011) Neurally adjusted ventilatory assist in patients with critical illness-associated polyneuromyopathy. Intensive Care Med 37:1951–1961
  14. Zapata L, Vera P, Roglan A, Gich I, Ordonez-Llanos J, Betbese AJ (2011) B-type natriuretic peptides for prediction and diagnosis of weaning failure from cardiac origin. Intensive Care Med 37:477–485
  15. Sellares J, Ferrer M, Cano E, Loureiro H, Valencia M, Torres A (2011) Predictors of prolonged weaning and survival during ventilator weaning in a respiratory ICU. Intensive Care Med 37:775–784
  16. Laghi F (2011) Stratification of difficulty in weaning. Intensive Care Med 37:732–734
  17. Fikkers BG, Staatsen M, van den Hoogen FJ, van der Hoeven JG (2011) Early and late outcome after single step dilatational tracheostomy versus the guide wire dilating forceps technique: a prospective randomized clinical trial. Intensive Care Med 37:1103–1109
  18. Zanella A, Scaravilli V, Isgro S, Milan M, Cressoni M, Patroniti N, Fumagalli R, Pesenti A (2011) Fluid leakage across tracheal tube cuff, effect of different cuff material, shape, and positive expiratory pressure: a bench-top study. Intensive Care Med 37:343–347
  19. Moran I, Cabello B, Manero E, Mancebo J (2011) Comparison of the effects of two humidifier systems on endotracheal tube resistance. Intensive Care Med 37:1773–1779
  20. Sinha P, Flower O, Soni N (2011) Deadspace ventilation: a waste of breath! Intensive Care Med 37:735–746
  21. Gancel PE, Roupie E, Guittet L, Laplume S, Terzi N (2011) Accuracy of a transcutaneous carbon dioxide pressure monitoring device in emergency room patients with acute respiratory failure. Intensive Care Med 37:348–351
  22. Barwing J, Pedroni C, Quintel M, Moerer O (2011) Influence of body position, PEEP and intra-abdominal pressure on the catheter positioning for neurally adjusted ventilatory assist. Intensive Care Med 37:2041–2045
  23. Demoule A, Morelot-Panzini C, Prodanovic H, Cracco C, Mayaux J, Duguet A, Similowski T (2011) Identification of prolonged phrenic nerve conduction time in the ICU: magnetic versus electrical stimulation. Intensive Care Med 37:1962–1968
  24. Chiumello D, Gallazzi E, Marino A, Berto V, Mietto C, Cesana B, Gattinoni L (2011) A validation study of a new nasogastric polyfunctional catheter. Intensive Care Med 37:791–795
  25. Spies C, Macguill M, Heymann A, Ganea C, Krahne D, Assman A, Kosiek HR, Scholtz K, Wernecke KD, Martin J (2011) A prospective, randomized, double-blind, multicenter study comparing remifentanil with fentanyl in mechanically ventilated patients. Intensive Care Med 37:469–476
  26. Clouzeau B, Bui HN, Guilhon E, Grenouillet-Delacre M, Leger MS, Saghi T, Pillot J, Filloux B, Coz S, Boyer A, Vargas F, Gruson D, Hilbert G (2011) Fiberoptic bronchoscopy under noninvasive ventilation and propofol target-controlled infusion in hypoxemic patients. Intensive Care Med 37:1969–1975
  27. Abreu SC, Antunes MA, Pelosi P, Morales MM, Rocco PR (2011) Mechanisms of cellular therapy in respiratory diseases. Intensive Care Med 37:1421–1431
  28. Caironi P, Langer T, Carlesso E, Protti A, Gattinoni L (2011) Time to generate ventilator-induced lung injury among mammals with healthy lungs: a unifying hypothesis. Intensive Care Med 37:1913–1920
  29. de Prost N, Saumon G, Dreyfuss D (2011) Modeling the time-course of ventilator-induced lung injury: what can we learn from interspecies discrepancies? Intensive Care Med 37:1901–1903
  30. Fodil R, Lellouche F, Mancebo J, Sbirlea-Apiou G, Isabey D, Brochard L, Louis B (2011) Comparison of patient–ventilator interfaces based on their computerized effective dead space. Intensive Care Med 37:257–262
  31. Cammarota G, Olivieri C, Costa R, Vaschetto R, Colombo D, Turucz E, Longhini F, Della Corte F, Conti G, Navalesi P (2011) Noninvasive ventilation through a helmet in postextubation hypoxemic patients: physiologic comparison between neurally adjusted ventilatory assist and pressure support ventilation. Intensive Care Med 37:1943–1950
  32. Milan M, Zanella A, Isgro S, Deab SA, Magni F, Pesenti A, Patroniti N (2011) Performance of different continuous positive airway pressure helmets equipped with safety valves during failure of fresh gas supply. Intensive Care Med 37:1031–1035
  33. Ducros L, Logeart D, Vicaut E, Henry P, Plaisance P, Collet JP, Broche C, Gueye P, Vergne M, Goetgheber D, Pennec PY, Belpomme V, Tartiere JM, Lagarde S, Placente M, Fievet ML, Montalescot G, Payen D (2011) CPAP for acute cardiogenic pulmonary oedema from out-of-hospital to cardiac intensive care unit: a randomised multicentre study. Intensive Care Med 37:1501–1509
  34. Nouira S, Boukef R, Bouida W, Kerkeni W, Beltaief K, Boubaker H, Boudhib L, Grissa MH, Trimech MN, Boussarsar H, Methamem M, Marghli S, Ltaief M (2011) Non-invasive pressure support ventilation and CPAP in cardiogenic pulmonary edema: a multicenter randomized study in the emergency department. Intensive Care Med 37:249–256
  35. L’Her E (2011) Is the noninvasive ventilatory mode of importance during cardiogenic pulmonary edema? Intensive Care Med 37:190–192
  36. Cammarota G, Vaschetto R, Turucz E, Dellapiazza F, Colombo D, Blando C, Della Corte F, Maggiore SM, Navalesi P (2011) Influence of lung collapse distribution on the physiologic response to recruitment maneuvers during noninvasive continuous positive airway pressure. Intensive Care Med 37:1095–1102
  37. Chiumello D, Chevallard G, Gregoretti C (2011) Non-invasive ventilation in postoperative patients: a systematic review. Intensive Care Med 37:918–929
  38. Azoulay E, Demoule A, Jaber S, Kouatchet A, Meert AP, Papazian L, Brochard L (2011) Palliative noninvasive ventilation in patients with acute respiratory failure. Intensive Care Med 37:1250–1257
  39. Dimassi S, Vargas F, Lyazidi A, Roche-Campo F, Dellamonica J, Brochard L (2011) Intrapulmonary percussive ventilation superimposed on spontaneous breathing: a physiological study in patients at risk for extubation failure. Intensive Care Med 37:1269–1276
  40. de Graaff AE, Dongelmans DA, Binnekade JM, de Jonge E (2011) Clinicians’ response to hyperoxia in ventilated patients in a Dutch ICU depends on the level of FiO2. Intensive Care Med 37:46–51
  41. Branson RD, Robinson BR (2011) Oxygen: when is more the enemy of good? Intensive Care Med 37:1–3
  42. Sztrymf B, Messika J, Bertrand F, Hurel D, Leon R, Dreyfuss D, Ricard JD (2011) Beneficial effects of humidified high flow nasal oxygen in critical care patients: a prospective pilot study. Intensive Care Med 37:1780–1786
  43. Visser DY, Jansen NJ, Ijland MM, de Koning TJ, van Hasselt PM (2011) Intracranial bleeding due to vitamin K deficiency: advantages of using a pediatric intensive care registry. Intensive Care Med 37:1014–1020
  44. Warrick C, Naik H, Avis S, Fletcher P, Franklin BD, Inwald D (2011) A clinical information system reduces medication errors in paediatric intensive care. Intensive Care Med 37:691–694
  45. Brown KL, Pagel C, Pienaar A, Utley M (2011) The relationship between workload and medical staffing levels in a paediatric cardiac intensive care unit. Intensive Care Med 37:326–333
  46. Latour JM, van Goudoever JB, Duivenvoorden HJ, Albers MJ, van Dam NA, Dullaart E, van Heerde M, de Neef M, Verlaat CW, van Vught EM, Hazelzet JA (2011) Construction and psychometric testing of the EMPATHIC questionnaire measuring parent satisfaction in the pediatric intensive care unit. Intensive Care Med 37:310–318
  47. Latour JM, van Goudoever JB, Schuurman BE, Albers MJ, van Dam NA, Dullaart E, van Heerde M, Verlaat CW, van Vught EM, Hazelzet JA (2011) A qualitative study exploring the experiences of parents of children admitted to seven Dutch pediatric intensive care units. Intensive Care Med 37:319–325
  48. Lopez-Herce J, Fernandez B, Urbano J, Mencia S, Solana MJ, Rodriguez-Nunez A, Bellon JM, Carrillo A (2011) Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrest. Intensive Care Med 37:147–155
  49. Botran M, Lopez-Herce J, Urbano J, Solana MJ, Garcia A, Carrillo A (2011) Chest compressions versus ventilation plus chest compressions: a randomized trial in a pediatric asphyxial cardiac arrest animal model. Intensive Care Med 37:1873–1880
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  52. Humpl T, Reyes JT, Erickson S, Armano R, Holtby H, Adatia I (2011) Sildenafil therapy for neonatal and childhood pulmonary hypertensive vascular disease. Cardiol Young 21:187–193
  53. Shah PS, Ohlsson A (2011) Sildenafil for pulmonary hypertension in neonates. Cochrane Database Syst Rev (8):CD005494
  54. Fraisse A, Butrous G, Taylor MB, Oakes M, Dilleen M, Wessel DL (2011) Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease. Intensive Care Med 37:502–509
  55. Hebbar KB, Stockwell JA, Fortenberry JD (2011) Clinical effects of adding fludrocortisone to a hydrocortisone-based shock protocol in hypotensive critically ill children. Intensive Care Med 37:518–524
  56. Hebbar KB, Stockwell JA, Leong T, Fortenberry JD (2011) Incidence of adrenal insufficiency and impact of corticosteroid supplementation in critically ill children with systemic inflammatory syndrome and vasopressor-dependent shock. Crit Care Med 39:1145–1150
  57. Kuhlwein E, Balmer C, Cannizzaro V, Frey B (2011) Determinants of arterial and central venous blood pressure variation in ventilated critically ill children. Intensive Care Med 37:118–123
  58. Teng S, Kaufman J, Pan Z, Czaja A, Shockley H, da Cruz E (2011) Continuous arterial pressure waveform monitoring in pediatric cardiac transplant, cardiomyopathy and pulmonary hypertension patients. Intensive Care Med 37:1297–1301
  59. Hockenhull JC, Dwan K, Boland A, Smith G, Bagust A, Dundar Y, Gamble C, McLeod C, Walley T, Dickson R (2008) The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation. Health Technology Assessment (Winchester, England) 12:iii–iv, xi–xii, 1–154
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  61. Niedner MF, Huskins WC, Colantuoni E, Muschelli J, Ii JM, Rice TB, Brilli RJ, Miller MR (2011) Epidemiology of central line-associated bloodstream infections in the pediatric intensive care unit. Infect Control Hosp Epidemiol 32:1200–1208
  62. Rey C, Alvarez F, De-La-Rua V, Concha A, Medina A, Diaz JJ, Menendez S, Los-Arcos M, Mayordomo-Colunga J (2011) Intervention to reduce catheter-related bloodstream infections in a pediatric intensive care unit. Intensive Care Med 37:678–685
  63. Roeleveld PP, Guijt D, Kuijper EJ, Hazekamp MG, de Wilde RB, de Jonge E (2011) Ventilator-associated pneumonia in children after cardiac surgery in the Netherlands. Intensive Care Med 37:1656–1663
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  65. Hall MW, Knatz NL, Vetterly C, Tomarello S, Wewers MD, Volk HD, Carcillo JA (2011) Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome. Intensive Care Med 37:525–532
  66. Janssen NJ, Tan EY, Staal M, Janssen EP, Leroy PL, Lousberg R, van Os J, Schieveld JN (2011) On the utility of diagnostic instruments for pediatric delirium in critical illness: an evaluation of the Pediatric Anesthesia Emergence Delirium Scale, the Delirium Rating Scale 88, and the Delirium Rating Scale-Revised R-98. Intensive Care Med 37:1331–1337
  67. Hoy SM, Keating GM (2011) Dexmedetomidine: a review of its use for sedation in mechanically ventilated patients in an intensive care setting and for procedural sedation. Drugs 71:1481–1501
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  68. Czaja AS, Zimmerman JJ (2009) The use of dexmedetomidine in critically ill children. Pediatric Critical Care Medicine 10:381–386
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  69. Le KN, Moffett BS, Ocampo EC, Zaki J, Mossad EB (2011) Impact of dexmedetomidine on early extubation in pediatric cardiac surgical patients. Intensive Care Med 37:686–690
  70. Tsapis M, Mignot C, Katsahian S, Arbaoui H, Ayachi A (2011) Case-control study of respiratory dynamic compliance in mechanically ventilated near-term newborns in a pre-hospital setting. Intensive Care Med 37:2008–2014
  71. Cogo PE, Facco M, Simonato M, De Luca D, De Terlizi F, Rizzotti U, Verlato G, Bellagamba MP, Carnielli VP (2011) Pharmacokinetics and clinical predictors of surfactant redosing in respiratory distress syndrome. Intensive Care Med 37:510–517
  72. Williams AM, Abramo TJ, Shah MV, Miller RA, Burney-Jones C, Rooks S, Estrada C, Arnold DH (2011) Safety and clinical findings of BiPAP utilization in children 20 kg or less for asthma exacerbations. Intensive Care Med 37:1338–1343
  73. James CS, Hallewell CP, James DP, Wade A, Mok QQ (2011) Predicting the success of non-invasive ventilation in preventing intubation and re-intubation in the paediatric intensive care unit. Intensive Care Med 37:1994–2001
  74. Piastra M, De Luca D, Marzano L, Stival E, Genovese O, Pietrini D, Conti G (2011) The number of failing organs predicts non-invasive ventilation failure in children with ALI/ARDS. Intensive Care Med 37:1510–1516
  75. Mayordomo-Colunga J, Medina A, Rey C, Diaz JJ, Concha A, Los M, Menendez S (2009) Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study. Intensive Care Med 35:527–536
  76. Essouri S, Durand P, Chevret L, Balu L, Devictor D, Fauroux B, Tissieres P (2011) Optimal level of nasal continuous positive airway pressure in severe viral bronchiolitis. Intensive Care Med 37:2002–2007
  77. Schibler A, Pham TM, Dunster KR, Foster K, Barlow A, Gibbons K, Hough JL (2011) Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery. Intensive Care Med 37:847–852
  78. De Luca D, Minucci A, Tripodi D, Piastra M, Pietrini D, Zuppi C, Conti G, Carnielli VP, Capoluongo E (2011) Role of distinct phospholipases A2 and their modulators in meconium aspiration syndrome in human neonates. Intensive Care Med 37:1158–1165
  79. Lubrano R, Cecchetti C, Elli M, Tomasello C, Guido G, Di Nardo M, Masciangelo R, Pasotti E, Barbieri MA, Bellelli E, Pirozzi N (2011) Prognostic value of extravascular lung water index in critically ill children with acute respiratory failure. Intensive Care Med 37:124–131
  80. Borik S, Simon AJ, Nevo-Caspi Y, Mishali D, Amariglio N, Rechavi G, Paret G (2011) Increased RNA editing in children with cyanotic congenital heart disease. Intensive Care Med 37:1664–1671
  81. Nevo-Caspi Y, Amariglio N, Rechavi G, Paret G (2011) A-to-I RNA editing is induced upon hypoxia. Shock 35:585–589
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  82. Hill H, Baines P, Barton P, Newland P, Terlouw D, Turner M (2011) Uncertainties in the measurement of blood glucose in paediatric intensive care: implications for clinical trials of tight glycaemic control. Intensive Care Med 37:1517–1524
  83. Selewski DT, Cornell TT, Lombel RM, Blatt NB, Han YY, Mottes T, Kommareddi M, Kershaw DB, Shanley TP, Heung M (2011) Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy. Intensive Care Med 37:1166–1173
  84. Carlesso E, Maiocchi G, Tallarini F, Polli F, Valenza F, Cadringher P, Gattinoni L (2011) The rule regulating pH changes during crystalloid infusion. Intensive Care Med 37:461–468
  85. Bonizzoli M, Batacchi S, Cianchi G, Zagli G, Lapi F, Tucci V, Martini G, Di Valvasone S, Peris A (2011) Peripherally inserted central venous catheters and central venous catheters related thrombosis in post-critical patients. Intensive Care Med 37:284–289
  86. De Keulenaer BL, Regli A, Dabrowski W, Kaloiani V, Bodnar Z, Cea JI, Litvin AA, Davis WA, Palermo AM, De Waele JJ, Malbrain ML (2011) Does femoral venous pressure measurement correlate well with intrabladder pressure measurement? A multicenter observational trial. Intensive Care Med 37:1620–1627
  87. Ho KM, Hart G, Austin D, Hunter M, Botha J, Chavan S (2011) Dose-related effect of smoking on mortality in critically ill patients: a multicentre cohort study. Intensive Care Med 37:981–989

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